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cediranib

cediranib

Synonyms

Sources	Names Used
CTRPv2	cediranib
PharmacoGx	cediranib

External IDs

Database	Identifier
Smiles:	COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1
Pubchem:	9933475

Annotated Targets

KIT, CSF1R, FLT1, FLT3, FLT4, KDR, PDGFRA, PDGFRB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to cediranib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DENND1C	CTRPv2	pan-cancer	AAC	0.21	0.001
mRNA	TARBP1	CTRPv2	pan-cancer	AAC	0.18	0.001
mRNA	MLLT10	CTRPv2	pan-cancer	AAC	0.19	0.001
mRNA	PBLD	CTRPv2	pan-cancer	AAC	0.17	0.001
mRNA	KTN1	CTRPv2	pan-cancer	AAC	-0.18	0.001
mRNA	LECT1	CTRPv2	pan-cancer	AAC	0.16	0.001
mRNA	TAS2R5	CTRPv2	pan-cancer	AAC	0.18	0.001
mRNA	PHKA2	CTRPv2	pan-cancer	AAC	0.18	0.001
mRNA	FAM182B	CTRPv2	pan-cancer	AAC	0.17	0.001
mRNA	MB21D1	CTRPv2	pan-cancer	AAC	0.18	0.001

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