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cediranib

cediranib

Synonyms

Sources	Names Used
CTRPv2	cediranib
PharmacoGx	cediranib

External IDs

Database	Identifier
Smiles:	COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1
Pubchem:	9933475

Annotated Targets

KIT, CSF1R, FLT1, FLT3, FLT4, KDR, PDGFRA, PDGFRB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to cediranib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GSX2	CTRPv2	pan-cancer	AAC	0.18	0.0005
mRNA	ARHGEF40	CTRPv2	pan-cancer	AAC	0.22	0.0005
mRNA	MARVELD1	CTRPv2	pan-cancer	AAC	0.22	0.0006
mRNA	TET1	CTRPv2	pan-cancer	AAC	0.2	0.0006
mRNA	TBC1D2B	CTRPv2	pan-cancer	AAC	0.18	0.0006
mRNA	PTEN	CTRPv2	pan-cancer	AAC	0.2	0.0006
mRNA	MS4A6A	CTRPv2	pan-cancer	AAC	0.18	0.0006
mRNA	ROGDI	CTRPv2	pan-cancer	AAC	0.2	0.0006
mRNA	BGN	CTRPv2	pan-cancer	AAC	0.18	0.0006
mRNA	FAM92B	CTRPv2	pan-cancer	AAC	0.18	0.0006

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