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WZ4002

WZ4002

Synonyms

Sources	Names Used
CTRPv2	WZ4002
PharmacoGx	WZ4002

External IDs

Database	Identifier
Smiles:	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(C)CC1
Pubchem:	44607530

Annotated Targets

EGFR, ERBB2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to WZ4002

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	C9orf69	CTRPv2	pan-cancer	AAC	0.097	0.03
mRNA	VPS9D1	CTRPv2	pan-cancer	AAC	0.098	0.03
mRNA	TMEM190	CTRPv2	pan-cancer	AAC	0.094	0.03
mRNA	TEX22	CTRPv2	pan-cancer	AAC	0.1	0.03
mRNA	IYD	CTRPv2	pan-cancer	AAC	0.1	0.03
mRNA	U2AF1L4	CTRPv2	pan-cancer	AAC	0.1	0.03
mRNA	C19orf18	CTRPv2	pan-cancer	AAC	0.094	0.03
mRNA	CASK	CTRPv2	pan-cancer	AAC	0.11	0.03
mRNA	RAI14	CTRPv2	pan-cancer	AAC	-0.11	0.03
mRNA	NLRP8	CTRPv2	pan-cancer	AAC	0.092	0.03

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