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WZ4002

WZ4002

Synonyms

Sources	Names Used
CTRPv2	WZ4002
PharmacoGx	WZ4002

External IDs

Database	Identifier
Smiles:	COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(C)CC1
Pubchem:	44607530

Annotated Targets

EGFR, ERBB2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to WZ4002

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CAMK2G	CTRPv2	pan-cancer	AAC	0.15	0.0009
mRNA	SOX4	CTRPv2	pan-cancer	AAC	0.14	0.0009
mRNA	APITD1	CTRPv2	pan-cancer	AAC	-0.15	0.0009
mRNA	SCNN1A	CTRPv2	pan-cancer	AAC	0.16	0.001
mRNA	EIF5AL1	CTRPv2	pan-cancer	AAC	-0.14	0.001
mRNA	SRD5A3	CTRPv2	pan-cancer	AAC	0.14	0.001
mRNA	EP300	CTRPv2	pan-cancer	AAC	0.15	0.001
mRNA	FBXO3	CTRPv2	pan-cancer	AAC	0.15	0.001
mRNA	GP2	CTRPv2	pan-cancer	AAC	0.14	0.001
mRNA	EPCAM	CTRPv2	pan-cancer	AAC	0.18	0.001

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