About
Documentation
Cite Us!
Github
Download
News
Explore
Batch Query
Search
Site
Home
About
Documentation
PharmacoGx
Cite Us!
Tools
Explore
Batch Query
Search
GitHub
Datatypes
datasets
cell lines
tissues
drugs
genes
experiments
Home
/
Compounds
/
AT-406
AT-406
Synonyms
Sources
Names Used
CTRPv2
AT-406
PharmacoGx
AT-406
External IDs
Database
Identifier
Pubchem:
25022340
Annotated Targets
XIAP
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with AT-406
(per dataset)
0
50
100
150
200
250
300
350
400
450
500
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
542
Download SVG
Number of tissues tested with AT-406 (per
dataset)
0
2
4
6
8
10
12
14
16
18
20
22
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
23
Download SVG
Dataset Select
all
CTRPv2
AT-406: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
0.45
0.50
KYM-1
KYM-1
MOLM-16
MOLM-16
Hs-578-T
Hs-578-T
GCT
GCT
M-07e
M-07e
TUHR10TKB
TUHR10TKB
SNU-398
SNU-398
BT-549
BT-549
SK-MM-2
SK-MM-2
EPLC-272H
EPLC-272H
Hs 944.T
Hs 944.T
SK-OV-3
SK-OV-3
ESS-1
ESS-1
KASUMI-1
KASUMI-1
IM-95
IM-95
EFM-192A
EFM-192A
A375
A375
Gp2D
Gp2D
MDA-MB-231
MDA-MB-231
COV644
COV644
RCH-ACV
RCH-ACV
Malme-3M
Malme-3M
DV-90
DV-90
EJM
EJM
NB4
NB4
NCI-H1105
NCI-H1105
Hs 852.T
Hs 852.T
BT-474
BT-474
OCI-LY3
OCI-LY3
NCI-H2228
NCI-H2228
HEC-1-A
HEC-1-A
BT232
BT232
BT504
BT504
HEC-151
HEC-151
BT147
BT147
BT333
BT333
KNS81
KNS81
ML-1
ML-1
NCI-H226
NCI-H226
TE-6
TE-6
TE-8
TE-8
KMS-11
KMS-11
KELLY
KELLY
SKM-1
SKM-1
OCI-AML2
OCI-AML2
Raji
Raji
PA-TU-8902
PA-TU-8902
SK-MEL-28
SK-MEL-28
KYSE-450
KYSE-450
CAL-27
CAL-27
HCC-56
HCC-56
Mino
Mino
HOP-62
HOP-62
KYSE-150
KYSE-150
BT172
BT172
BT271
BT271
BT320
BT320
BT330
BT330
BT340
BT340
BT444
BT444
KYM-1
MOLM-16
Hs-578-T
GCT
M-07e
TUHR10TKB
SNU-398
BT-549
SK-MM-2
EPLC-272H
Hs 944.T
SK-OV-3
ESS-1
KASUMI-1
IM-95
EFM-192A
A375
Gp2D
MDA-MB-231
COV644
RCH-ACV
Malme-3M
DV-90
EJM
NB4
NCI-H1105
Hs 852.T
BT-474
OCI-LY3
NCI-H2228
HEC-1-A
BT232
BT504
HEC-151
BT147
BT333
KNS81
ML-1
NCI-H226
TE-6
TE-8
KMS-11
KELLY
SKM-1
OCI-AML2
Raji
PA-TU-8902
SK-MEL-28
KYSE-450
CAL-27
HCC-56
Mino
HOP-62
KYSE-150
BT172
BT271
BT320
BT330
BT340
BT444
KYM-1: 0.53
Synonyms: KYM-1, KYM1
MOLM-16: 0.51
Synonyms: MOLM-16, MOLM16
Hs-578-T: 0.44
Synonyms: Hs-578-T, Hs 578T, Hs_578T, HS578T, hs578t
GCT: 0.42
Synonyms: GCT
M-07e: 0.40
Synonyms: M-07e, M07E
TUHR10TKB: 0.37
Synonyms: TUHR10TKB
SNU-398: 0.33
Synonyms: SNU-398, SNU398
BT-549: 0.32
Synonyms: BT-549, BT549, bt549
SK-MM-2: 0.32
Synonyms: SK-MM-2, SKMM2
EPLC-272H: 0.32
Synonyms: EPLC-272H, EPLC272H
Hs 944.T: 0.31
Synonyms: Hs 944.T, Hs_944.T, Hs-944-T, HS944T
SK-OV-3: 0.31
Synonyms: SK-OV-3, SKOV3
ESS-1: 0.30
Synonyms: ESS-1, ESS1
KASUMI-1: 0.29
Synonyms: KASUMI-1, Kasumi-1, KASUMI1
IM-95: 0.29
Synonyms: IM-95, IM95
EFM-192A: 0.29
Synonyms: EFM-192A, EFM192A, efm192a
A375: 0.29
Synonyms: A375, A-375
Gp2D: 0.28
Synonyms: Gp2D, GP2d, GP2D
MDA-MB-231: 0.28
Synonyms: MDA-MB-231, MDAMB231, mdamb231
COV644: 0.28
Synonyms: COV644
RCH-ACV: 0.27
Synonyms: RCH-ACV, RCHACV
Malme-3M: 0.27
Synonyms: Malme-3M, MALME3M
DV-90: 0.27
Synonyms: DV-90, DV90
EJM: 0.26
Synonyms: EJM
NB4: 0.26
Synonyms: NB4, NB-4
NCI-H1105: 0.25
Synonyms: NCI-H1105, NCIH1105
Hs 852.T: 0.25
Synonyms: Hs 852.T, Hs_852.T, HS852T
BT-474: 0.24
Synonyms: BT-474, BT474, bt474
OCI-LY3: 0.23
Synonyms: OCI-LY3, OCI-LY-3, OCILY3
NCI-H2228: 0.23
Synonyms: NCI-H2228, NCIH2228
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
HEC-1-A: 0.00
Synonyms: HEC-1-A, HEC1A
BT232: 0.00
Synonyms: BT232
BT504: 0.00
Synonyms: BT504
HEC-151: 0.00
Synonyms: HEC-151, HEC151
BT147: 0.00
Synonyms: BT147
BT333: 0.00
Synonyms: BT333
KNS81: 0.00
Synonyms: KNS81
ML-1: 0.00
Synonyms: ML-1, ML1
NCI-H226: 0.00
Synonyms: NCI-H226, NCIH226
TE-6: 0.00
Synonyms: TE-6, TE6
TE-8: 0.00
Synonyms: TE-8, TE8
KMS-11: 0.00
Synonyms: KMS-11, KMS11
KELLY: 0.00
Synonyms: KELLY
SKM-1: 0.00
Synonyms: SKM-1, SKM1
OCI-AML2: 0.00
Synonyms: OCI-AML2, OCIAML2
Raji: 0.00
Synonyms: Raji, RAJI
PA-TU-8902: 0.00
Synonyms: PA-TU-8902, PATU8902
SK-MEL-28: 0.00
Synonyms: SK-MEL-28, SKMEL28
KYSE-450: 0.00
Synonyms: KYSE-450, KYSE450
CAL-27: 0.00
Synonyms: CAL-27, CAL 27, CAL_27, CAL27
HCC-56: 0.00
Synonyms: HCC-56, HCC56
Mino: 0.00
Synonyms: Mino, MINO
HOP-62: 0.00
Synonyms: HOP-62, HOP62
KYSE-150: 0.00
Synonyms: KYSE-150, KYSE150
BT172: 0.00
Synonyms: BT172
BT271: 0.00
Synonyms: BT271
BT320: 0.00
Synonyms: BT320
BT330: 0.00
Synonyms: BT330
BT340: 0.00
Synonyms: BT340
BT444: 0.00
Synonyms: BT444
Download SVG
0.00
2.00
4.00
6.00
8.00
10.00
12.00
14.00
16.00
RPMI-6666
RPMI-6666
SNU-61
SNU-61
SW1116
SW1116
HT-1376
HT-1376
GRANTA-519
GRANTA-519
SCC-9
SCC-9
NCI-H1105
NCI-H1105
NCI-H1184
NCI-H1184
KASUMI-2
KASUMI-2
THP-1
THP-1
BC-3C
BC-3C
A549
A549
LC-1/sq-SF
LC-1/sq-SF
NCI-H2029
NCI-H2029
K029AX
K029AX
BICR 31
BICR 31
TE-5
TE-5
ME-1
ME-1
PE/CA-PJ34 (clone C12)
PE/CA-PJ34 (clone C12)
LS-1034
LS-1034
RCH-ACV
RCH-ACV
MHH-CALL-3
MHH-CALL-3
SNU-C5
SNU-C5
BICR 6
BICR 6
VMRC-RCW
VMRC-RCW
BT224
BT224
SF268
SF268
HSC-2
HSC-2
MES-SA
MES-SA
DV-90
DV-90
COV644
COV644
NCI-H522
NCI-H522
SW1573
SW1573
CAL-33
CAL-33
Sq-1
Sq-1
MDA-MB-157
MDA-MB-157
Caov-3
Caov-3
KE-39
KE-39
LS-123
LS-123
Hs 944.T
Hs 944.T
OVCAR-4
OVCAR-4
HT-1080
HT-1080
SR-786
SR-786
BT-549
BT-549
EPLC-272H
EPLC-272H
SK-MM-2
SK-MM-2
KMBC-2
KMBC-2
LOXIMVI
LOXIMVI
8-MG-BA
8-MG-BA
MDA-MB-231
MDA-MB-231
Hs 852.T
Hs 852.T
NB4
NB4
A375
A375
ESS-1
ESS-1
SK-OV-3
SK-OV-3
TUHR10TKB
TUHR10TKB
Hs-578-T
Hs-578-T
M-07e
M-07e
MOLM-16
MOLM-16
GCT
GCT
RPMI-6666
SNU-61
SW1116
HT-1376
GRANTA-519
SCC-9
NCI-H1105
NCI-H1184
KASUMI-2
THP-1
BC-3C
A549
LC-1/sq-SF
NCI-H2029
K029AX
BICR 31
TE-5
ME-1
PE/CA-PJ34 (clone C12)
LS-1034
RCH-ACV
MHH-CALL-3
SNU-C5
BICR 6
VMRC-RCW
BT224
SF268
HSC-2
MES-SA
DV-90
COV644
NCI-H522
SW1573
CAL-33
Sq-1
MDA-MB-157
Caov-3
KE-39
LS-123
Hs 944.T
OVCAR-4
HT-1080
SR-786
BT-549
EPLC-272H
SK-MM-2
KMBC-2
LOXIMVI
8-MG-BA
MDA-MB-231
Hs 852.T
NB4
A375
ESS-1
SK-OV-3
TUHR10TKB
Hs-578-T
M-07e
MOLM-16
GCT
RPMI-6666: 15.97 (log10 µM)
Synonyms: RPMI-6666, RPMI6666
SNU-61: 15.68 (log10 µM)
Synonyms: SNU-61, SNU61
SW1116: 12.83 (log10 µM)
Synonyms: SW1116, SW 1116
HT-1376: 10.16 (log10 µM)
Synonyms: HT-1376, HT1376
GRANTA-519: 9.84 (log10 µM)
Synonyms: GRANTA-519, GRANTA519
SCC-9: 8.74 (log10 µM)
Synonyms: SCC-9, SCC9
NCI-H1105: 8.46 (log10 µM)
Synonyms: NCI-H1105, NCIH1105
NCI-H1184: 8.44 (log10 µM)
Synonyms: NCI-H1184, NCIH1184
KASUMI-2: 8.40 (log10 µM)
Synonyms: KASUMI-2, KASUMI2
THP-1: 8.36 (log10 µM)
Synonyms: THP-1, THP1
BC-3C: 8.36 (log10 µM)
Synonyms: BC-3C, BC3C
A549: 8.19 (log10 µM)
Synonyms: A549
LC-1/sq-SF: 7.89 (log10 µM)
Synonyms: LC-1/sq-SF, LC1SQSF
NCI-H2029: 7.88 (log10 µM)
Synonyms: NCI-H2029, NCIH2029
K029AX: 7.50 (log10 µM)
Synonyms: K029AX
BICR 31: 6.86 (log10 µM)
Synonyms: BICR 31, BICR_31, BICR31
TE-5: 6.61 (log10 µM)
Synonyms: TE-5, TE5
ME-1: 6.50 (log10 µM)
Synonyms: ME-1, ME1
PE/CA-PJ34 (clone C12): 6.29 (log10 µM)
Synonyms: PE/CA-PJ34 (clone C12), PE_CA-PJ34__clone_C12_, PECAPJ34CLONEC12
LS-1034: 6.09 (log10 µM)
Synonyms: LS-1034, LS1034
RCH-ACV: 6.00 (log10 µM)
Synonyms: RCH-ACV, RCHACV
MHH-CALL-3: 6.00 (log10 µM)
Synonyms: MHH-CALL-3, MHHCALL3
SNU-C5: 6.00 (log10 µM)
Synonyms: SNU-C5, SNUC5
BICR 6: 6.00 (log10 µM)
Synonyms: BICR 6, BICR_6, BICR6
VMRC-RCW: 6.00 (log10 µM)
Synonyms: VMRC-RCW, VMRCRCW
BT224: 5.83 (log10 µM)
Synonyms: BT224
SF268: 5.77 (log10 µM)
Synonyms: SF268
HSC-2: 5.50 (log10 µM)
Synonyms: HSC-2, HSC2
MES-SA: 5.41 (log10 µM)
Synonyms: MES-SA, MESSA
DV-90: 5.36 (log10 µM)
Synonyms: DV-90, DV90
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
COV644: 1.59 (log10 µM)
Synonyms: COV644
NCI-H522: 1.59 (log10 µM)
Synonyms: NCI-H522, NCIH522
SW1573: 1.57 (log10 µM)
Synonyms: SW1573, SW 1573, SW_1573
CAL-33: 1.57 (log10 µM)
Synonyms: CAL-33, CAL33
Sq-1: 1.50 (log10 µM)
Synonyms: Sq-1, SQ1
MDA-MB-157: 1.49 (log10 µM)
Synonyms: MDA-MB-157, MDAMB157, mdamb157
Caov-3: 1.49 (log10 µM)
Synonyms: Caov-3, CAOV3
KE-39: 1.49 (log10 µM)
Synonyms: KE-39, KE39
LS-123: 1.48 (log10 µM)
Synonyms: LS-123, LS123
Hs 944.T: 1.37 (log10 µM)
Synonyms: Hs 944.T, Hs_944.T, Hs-944-T, HS944T
OVCAR-4: 1.36 (log10 µM)
Synonyms: OVCAR-4, OVCAR4
HT-1080: 1.35 (log10 µM)
Synonyms: HT-1080, HT1080
SR-786: 1.32 (log10 µM)
Synonyms: SR-786, SR786
BT-549: 1.27 (log10 µM)
Synonyms: BT-549, BT549, bt549
EPLC-272H: 1.20 (log10 µM)
Synonyms: EPLC-272H, EPLC272H
SK-MM-2: 1.04 (log10 µM)
Synonyms: SK-MM-2, SKMM2
KMBC-2: 1.01 (log10 µM)
Synonyms: KMBC-2, KMBC2
LOXIMVI: 0.92 (log10 µM)
Synonyms: LOXIMVI, LOX IMVI, LOX_IMVI, LOX-IMVI
8-MG-BA: 0.89 (log10 µM)
Synonyms: 8-MG-BA, 8MGBA
MDA-MB-231: 0.83 (log10 µM)
Synonyms: MDA-MB-231, MDAMB231, mdamb231
Hs 852.T: 0.71 (log10 µM)
Synonyms: Hs 852.T, Hs_852.T, HS852T
NB4: 0.62 (log10 µM)
Synonyms: NB4, NB-4
A375: 0.57 (log10 µM)
Synonyms: A375, A-375
ESS-1: 0.42 (log10 µM)
Synonyms: ESS-1, ESS1
SK-OV-3: 0.40 (log10 µM)
Synonyms: SK-OV-3, SKOV3
TUHR10TKB: 0.31 (log10 µM)
Synonyms: TUHR10TKB
Hs-578-T: -0.00 (log10 µM)
Synonyms: Hs-578-T, Hs 578T, Hs_578T, HS578T, hs578t
M-07e: -0.04 (log10 µM)
Synonyms: M-07e, M07E
MOLM-16: -0.24 (log10 µM)
Synonyms: MOLM-16, MOLM16
GCT: -0.37 (log10 µM)
Synonyms: GCT
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
AT-406: AAC
AAC
Tissues
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
0.45
0.50
cervix
cervix
unknown
unknown
pleura
pleura
pancreas
pancreas
bone
bone
oesophagus
oesophagus
prostate
prostate
liver
liver
stomach
stomach
endometrium
endometrium
skin
skin
central_nervous_system
central_nervous_system
soft_tissue
soft_tissue
thyroid
thyroid
ovary
ovary
autonomic_ganglia
autonomic_ganglia
lung
lung
large_intestine
large_intestine
breast
breast
urinary_tract
urinary_tract
upper_aerodigestive_tract
upper_aerodigestive_tract
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
kidney
kidney
0.00
1.00
2.00
3.00
4.00
5.00
6.00
7.00
8.00
9.00
cervix
cervix
breast
breast
ovary
ovary
stomach
stomach
soft_tissue
soft_tissue
prostate
prostate
pleura
pleura
unknown
unknown
bone
bone
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
liver
liver
central_nervous_system
central_nervous_system
skin
skin
urinary_tract
urinary_tract
pancreas
pancreas
oesophagus
oesophagus
thyroid
thyroid
lung
lung
large_intestine
large_intestine
upper_aerodigestive_tract
upper_aerodigestive_tract
autonomic_ganglia
autonomic_ganglia
endometrium
endometrium
kidney
kidney
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to AT-406
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
SCG5
CTRPv2
pan-cancer
AAC
0.1
0.04
mRNA
FREM1
CTRPv2
pan-cancer
AAC
0.093
0.04
mRNA
SZT2
CTRPv2
pan-cancer
AAC
0.098
0.04
mRNA
TMEM186
CTRPv2
pan-cancer
AAC
-0.098
0.04
mRNA
TMPPE
CTRPv2
pan-cancer
AAC
0.099
0.04
mRNA
INSR
CTRPv2
pan-cancer
AAC
0.1
0.04
mRNA
ANXA5
CTRPv2
pan-cancer
AAC
-0.13
0.04
mRNA
ZC3H10
CTRPv2
pan-cancer
AAC
0.1
0.04
mRNA
IMP3
CTRPv2
pan-cancer
AAC
-0.098
0.04
mRNA
DHCR24
CTRPv2
pan-cancer
AAC
-0.11
0.04
← Previous
1
2
…
162
163
164
…
199
200
Next →
Download CSV