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ibrutinib

ibrutinib

Synonyms

Sources	Names Used
CTRPv2	ibrutinib
PharmacoGx	ibrutinib

External IDs

Database	Identifier
Smiles:	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem:	24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to ibrutinib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZYX	CTRPv2	pan-cancer	AAC	-0.093	0.03
mRNA	ZSCAN29	CTRPv2	pan-cancer	AAC	0.11	0.02
mRNA	ZSCAN26	CTRPv2	pan-cancer	AAC	-0.13	0.002
mRNA	ZSCAN16	CTRPv2	pan-cancer	AAC	0.12	0.008
mRNA	ZRSR2	CTRPv2	pan-cancer	AAC	0.12	0.008
mRNA	ZPBP2	CTRPv2	pan-cancer	AAC	0.16	0.0001
mRNA	ZNRF2	CTRPv2	pan-cancer	AAC	0.11	0.01
mRNA	ZNF865	CTRPv2	pan-cancer	AAC	0.095	0.02
mRNA	ZNF860	CTRPv2	pan-cancer	AAC	0.21	5e-07
mRNA	ZNF837	CTRPv2	pan-cancer	AAC	0.14	0.001

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