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ibrutinib

ibrutinib

Synonyms

Sources	Names Used
CTRPv2	ibrutinib
PharmacoGx	ibrutinib

External IDs

Database	Identifier
Smiles:	Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem:	24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to ibrutinib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ARHGAP11A	CTRPv2	pan-cancer	AAC	-0.098	0.02
mRNA	UBR5	CTRPv2	pan-cancer	AAC	0.1	0.02
mRNA	OR52N4	CTRPv2	pan-cancer	AAC	0.1	0.02
mRNA	CPT2	CTRPv2	pan-cancer	AAC	0.098	0.02
mRNA	PASK	CTRPv2	pan-cancer	AAC	0.099	0.02
mRNA	MCAT	CTRPv2	pan-cancer	AAC	0.097	0.02
mRNA	LSM12	CTRPv2	pan-cancer	AAC	-0.098	0.02
mRNA	XRCC3	CTRPv2	pan-cancer	AAC	0.1	0.02
mRNA	EIF4A3	CTRPv2	pan-cancer	AAC	0.095	0.02
mRNA	VIPAS39	CTRPv2	pan-cancer	AAC	0.099	0.02

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