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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA GART CTRPv2 pan-cancer AAC -0.094 0.03
mRNA MTG2 CTRPv2 pan-cancer AAC -0.093 0.03
mRNA CST9 CTRPv2 pan-cancer AAC -0.094 0.03
mRNA PBX1 CTRPv2 pan-cancer AAC 0.11 0.03
mRNA KLC3 CTRPv2 pan-cancer AAC 0.1 0.03
mRNA RMDN3 CTRPv2 pan-cancer AAC 0.091 0.03
mRNA GABARAPL1 CTRPv2 pan-cancer AAC -0.096 0.03
mRNA MMGT1 CTRPv2 pan-cancer AAC -0.092 0.03
mRNA MAST3 CTRPv2 pan-cancer AAC 0.11 0.03
mRNA SQSTM1 CTRPv2 pan-cancer AAC -0.097 0.03
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