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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA SYF2 CTRPv2 pan-cancer AAC -0.1 0.03
mRNA MFAP1 CTRPv2 pan-cancer AAC 0.092 0.03
mRNA BTNL9 CTRPv2 pan-cancer AAC 0.092 0.03
mRNA TAF11 CTRPv2 pan-cancer AAC 0.098 0.03
mRNA ALS2 CTRPv2 pan-cancer AAC -0.095 0.03
mRNA FBXL19 CTRPv2 pan-cancer AAC 0.097 0.03
mRNA TERF2 CTRPv2 pan-cancer AAC 0.1 0.03
mRNA SUB1 CTRPv2 pan-cancer AAC -0.095 0.03
mRNA MX1 CTRPv2 pan-cancer AAC 0.092 0.03
mRNA RPL35A CTRPv2 pan-cancer AAC -0.097 0.03
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