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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA NECTIN4 CTRPv2 pan-cancer AAC 0.19 6e-05
mRNA CYP39A1 CTRPv2 pan-cancer AAC 0.16 6e-05
mRNA FAM171B CTRPv2 pan-cancer AAC 0.17 6e-05
mRNA OR13A1 CTRPv2 pan-cancer AAC 0.17 6e-05
mRNA SGSM3 CTRPv2 pan-cancer AAC 0.18 6e-05
mRNA SP140 CTRPv2 pan-cancer AAC 0.18 6e-05
mRNA CDS1 CTRPv2 pan-cancer AAC 0.2 6e-05
mRNA BUB1B-PAK6 CTRPv2 pan-cancer AAC 0.17 7e-05
mRNA FCRLA CTRPv2 pan-cancer AAC 0.18 7e-05
mRNA SREBF1 CTRPv2 pan-cancer AAC 0.17 7e-05
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