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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA PRODH CTRPv2 pan-cancer AAC 0.093 0.03
mRNA EFHD1 CTRPv2 pan-cancer AAC 0.12 0.03
mRNA C17orf51 CTRPv2 pan-cancer AAC -0.096 0.03
mRNA GPIHBP1 CTRPv2 pan-cancer AAC -0.09 0.03
mRNA OXER1 CTRPv2 pan-cancer AAC 0.093 0.03
mRNA HGH1 CTRPv2 pan-cancer AAC 0.096 0.03
mRNA AFF3 CTRPv2 pan-cancer AAC 0.099 0.03
mRNA RAB2A CTRPv2 pan-cancer AAC -0.1 0.03
mRNA DLC1 CTRPv2 pan-cancer AAC -0.096 0.03
mRNA NUFIP2 CTRPv2 pan-cancer AAC 0.093 0.03
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