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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA CTNNA3 CTRPv2 pan-cancer AAC 0.16 7e-05
mRNA CARD11 CTRPv2 pan-cancer AAC 0.18 7e-05
mRNA AC022405.1 CTRPv2 pan-cancer AAC 0.17 7e-05
mRNA GRB7 CTRPv2 pan-cancer AAC 0.17 7e-05
mRNA TRIM22 CTRPv2 pan-cancer AAC 0.18 7e-05
mRNA ZCCHC2 CTRPv2 pan-cancer AAC 0.17 7e-05
mRNA MAL2 CTRPv2 pan-cancer AAC 0.19 7e-05
mRNA BLNK CTRPv2 pan-cancer AAC 0.18 7e-05
mRNA TOB1 CTRPv2 pan-cancer AAC 0.18 8e-05
mRNA MT-CO2 CTRPv2 pan-cancer AAC 0.19 8e-05
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