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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA CNR2 CTRPv2 pan-cancer AAC 0.18 5e-05
mRNA SLC5A10 CTRPv2 pan-cancer AAC 0.19 5e-05
mRNA VCX3A CTRPv2 pan-cancer AAC 0.17 5e-05
mRNA RABGAP1L CTRPv2 pan-cancer AAC 0.19 5e-05
mRNA AIM1 CTRPv2 pan-cancer AAC 0.18 5e-05
mRNA NFATC1 CTRPv2 pan-cancer AAC 0.18 5e-05
mRNA KLF5 CTRPv2 pan-cancer AAC 0.22 5e-05
mRNA SP110 CTRPv2 pan-cancer AAC 0.18 5e-05
mRNA APBB1IP CTRPv2 pan-cancer AAC 0.21 5e-05
mRNA P2RY2 CTRPv2 pan-cancer AAC 0.18 5e-05
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