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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA CD79B CTRPv2 pan-cancer AAC 0.25 2e-08
mRNA ALDH5A1 CTRPv2 pan-cancer AAC 0.24 5e-08
mRNA RHOH CTRPv2 pan-cancer AAC 0.27 6e-08
mRNA NEK8 CTRPv2 pan-cancer AAC 0.23 7e-08
mRNA S100A14 CTRPv2 pan-cancer AAC 0.25 7e-08
mRNA ZC3H12D CTRPv2 pan-cancer AAC 0.25 1e-07
mRNA CDK12 CTRPv2 pan-cancer AAC 0.22 2e-07
mRNA BCAS4 CTRPv2 pan-cancer AAC 0.22 2e-07
mRNA TNFRSF13C CTRPv2 pan-cancer AAC 0.23 2e-07
mRNA N4BP3 CTRPv2 pan-cancer AAC 0.22 2e-07
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