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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA FASN CTRPv2 pan-cancer AAC 0.2 1e-05
mRNA GSDMB CTRPv2 pan-cancer AAC 0.19 1e-05
mRNA CCDC69 CTRPv2 pan-cancer AAC 0.22 1e-05
mRNA TTC9 CTRPv2 pan-cancer AAC 0.19 1e-05
mRNA PRH1 CTRPv2 pan-cancer AAC -0.18 1e-05
mRNA FCRL1 CTRPv2 pan-cancer AAC 0.18 1e-05
mRNA STIM2 CTRPv2 pan-cancer AAC 0.19 1e-05
mRNA TEX13B CTRPv2 pan-cancer AAC 0.18 1e-05
mRNA ADGRF4 CTRPv2 pan-cancer AAC 0.2 1e-05
mRNA HLA-DOA CTRPv2 pan-cancer AAC 0.19 1e-05
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