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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA ERBB2 CTRPv2 pan-cancer AAC 0.29 7e-11
mRNA SMIM14 CTRPv2 pan-cancer AAC 0.26 7e-10
mRNA CYB561A3 CTRPv2 pan-cancer AAC 0.26 8e-10
mRNA NCOA3 CTRPv2 pan-cancer AAC 0.25 1e-09
mRNA BCL7A CTRPv2 pan-cancer AAC 0.28 1e-09
mRNA STARD3 CTRPv2 pan-cancer AAC 0.27 2e-09
mRNA MS4A1 CTRPv2 pan-cancer AAC 0.26 2e-09
mRNA ZNF296 CTRPv2 pan-cancer AAC 0.3 4e-09
mRNA TRAF4 CTRPv2 pan-cancer AAC 0.25 1e-08
mRNA HLA-DMB CTRPv2 pan-cancer AAC 0.24 2e-08
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