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ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

FDA Approval Status

Approved
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Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA ZHX3 CTRPv2 pan-cancer AAC -0.15 0.0005
mRNA CTC-490E21.12 CTRPv2 pan-cancer AAC 0.15 0.0005
mRNA BCAM CTRPv2 pan-cancer AAC 0.16 0.0005
mRNA CYP2W1 CTRPv2 pan-cancer AAC 0.15 0.0005
mRNA SLAMF6 CTRPv2 pan-cancer AAC 0.15 0.0006
mRNA HLA-DPA1 CTRPv2 pan-cancer AAC 0.15 0.0006
mRNA TAS2R20 CTRPv2 pan-cancer AAC -0.14 0.0006
mRNA C1orf64 CTRPv2 pan-cancer AAC 0.16 0.0006
mRNA TEX37 CTRPv2 pan-cancer AAC 0.14 0.0006
mRNA CPT1B CTRPv2 pan-cancer AAC 0.16 0.0006
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