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BRD-K09344309
BRD-K09344309
Synonyms
Sources
Names Used
CTRPv2
BRD-K09344309
PharmacoGx
BRD-K09344309
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with
BRD-K09344309 (per dataset)
0
20
40
60
80
100
120
140
160
180
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
187
Download SVG
Number of tissues tested with
BRD-K09344309 (per dataset)
0
2
4
6
8
10
12
14
16
18
20
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
20
Download SVG
Dataset Select
all
CTRPv2
BRD-K09344309: AAC
AAC
0.00
0.02
0.04
0.06
0.08
0.10
0.12
0.14
0.16
0.18
0.20
0.22
CAL-78
CAL-78
JK-1
JK-1
KM12
KM12
MCAS
MCAS
KELLY
KELLY
NCI-H2122
NCI-H2122
SNG-M
SNG-M
HEC-50B
HEC-50B
NCI-H460
NCI-H460
HeLa
HeLa
OCI-AML2
OCI-AML2
SW1573
SW1573
FU-OV-1
FU-OV-1
IGROV-1
IGROV-1
NCI-H446
NCI-H446
HUH-6-clone5
HUH-6-clone5
NCI-H508
NCI-H508
NB4
NB4
L3.3
L3.3
KARPAS-299
KARPAS-299
Calu-6
Calu-6
HT-1376
HT-1376
HT55
HT55
MKN74
MKN74
RT-112
RT-112
SKM-1
SKM-1
Hep G2
Hep G2
PA-TU-8902
PA-TU-8902
MSTO-211H
MSTO-211H
SNU-886
SNU-886
KARPAS-620
KARPAS-620
NCI-H1666
NCI-H1666
SCC-25
SCC-25
SU-DHL-4
SU-DHL-4
NCI-H2052
NCI-H2052
NCI-H1792
NCI-H1792
OVCAR-4
OVCAR-4
COLO 201
COLO 201
Raji
Raji
REH
REH
SNU-840
SNU-840
SW1088
SW1088
SK-MEL-5
SK-MEL-5
Caov-3
Caov-3
HuP-T4
HuP-T4
NCI-H1755
NCI-H1755
VMRC-RCW
VMRC-RCW
LoVo
LoVo
MDA-MB-435
MDA-MB-435
A375
A375
RMG-I
RMG-I
WM-793
WM-793
KYSE-70
KYSE-70
LXF-289
LXF-289
NCI-H1435
NCI-H1435
NCI-H2023
NCI-H2023
NCI-H2126
NCI-H2126
NUGC-3
NUGC-3
TCC-PAN2
TCC-PAN2
YAPC
YAPC
CAL-78
JK-1
KM12
MCAS
KELLY
NCI-H2122
SNG-M
HEC-50B
NCI-H460
HeLa
OCI-AML2
SW1573
FU-OV-1
IGROV-1
NCI-H446
HUH-6-clone5
NCI-H508
NB4
L3.3
KARPAS-299
Calu-6
HT-1376
HT55
MKN74
RT-112
SKM-1
Hep G2
PA-TU-8902
MSTO-211H
SNU-886
KARPAS-620
NCI-H1666
SCC-25
SU-DHL-4
NCI-H2052
NCI-H1792
OVCAR-4
COLO 201
Raji
REH
SNU-840
SW1088
SK-MEL-5
Caov-3
HuP-T4
NCI-H1755
VMRC-RCW
LoVo
MDA-MB-435
A375
RMG-I
WM-793
KYSE-70
LXF-289
NCI-H1435
NCI-H2023
NCI-H2126
NUGC-3
TCC-PAN2
YAPC
CAL-78: 0.22
Synonyms: CAL-78, CAL78
JK-1: 0.15
Synonyms: JK-1, JK1
KM12: 0.13
Synonyms: KM12, KM-12
MCAS: 0.12
Synonyms: MCAS
KELLY: 0.12
Synonyms: KELLY
NCI-H2122: 0.12
Synonyms: NCI-H2122, NCIH2122
SNG-M: 0.11
Synonyms: SNG-M, SNGM
HEC-50B: 0.11
Synonyms: HEC-50B, HEC50B
NCI-H460: 0.11
Synonyms: NCI-H460, NCIH460
HeLa: 0.10
Synonyms: HeLa, HELA
OCI-AML2: 0.10
Synonyms: OCI-AML2, OCIAML2
SW1573: 0.10
Synonyms: SW1573, SW 1573, SW_1573
FU-OV-1: 0.09
Synonyms: FU-OV-1, FUOV1
IGROV-1: 0.08
Synonyms: IGROV-1, IGROV1
NCI-H446: 0.08
Synonyms: NCI-H446, NCIH446
HUH-6-clone5: 0.08
Synonyms: HUH-6-clone5, HuH-6, HUH6
NCI-H508: 0.07
Synonyms: NCI-H508, NCIH508
NB4: 0.07
Synonyms: NB4, NB-4
L3.3: 0.07
Synonyms: L3.3, L33
KARPAS-299: 0.07
Synonyms: KARPAS-299, KARPAS299
Calu-6: 0.06
Synonyms: Calu-6, CALU6
HT-1376: 0.06
Synonyms: HT-1376, HT1376
HT55: 0.06
Synonyms: HT55, HT-55
MKN74: 0.06
Synonyms: MKN74, MKN-74
RT-112: 0.06
Synonyms: RT-112, RT112
SKM-1: 0.06
Synonyms: SKM-1, SKM1
Hep G2: 0.05
Synonyms: Hep G2, Hep_G2, HEPG2
PA-TU-8902: 0.05
Synonyms: PA-TU-8902, PATU8902
MSTO-211H: 0.05
Synonyms: MSTO-211H, MSTO211H
SNU-886: 0.05
Synonyms: SNU-886, SNU886
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
KARPAS-620: 0.00
Synonyms: KARPAS-620, KARPAS620
NCI-H1666: 0.00
Synonyms: NCI-H1666, NCIH1666
SCC-25: 0.00
Synonyms: SCC-25, SCC25
SU-DHL-4: 0.00
Synonyms: SU-DHL-4, SUDHL4
NCI-H2052: 0.00
Synonyms: NCI-H2052, NCIH2052
NCI-H1792: 0.00
Synonyms: NCI-H1792, NCIH1792
OVCAR-4: 0.00
Synonyms: OVCAR-4, OVCAR4
COLO 201: 0.00
Synonyms: COLO 201, COLO_201, COLO201
Raji: 0.00
Synonyms: Raji, RAJI
REH: 0.00
Synonyms: REH, Reh
SNU-840: 0.00
Synonyms: SNU-840, SNU840
SW1088: 0.00
Synonyms: SW1088, SW 1088, SW_1088
SK-MEL-5: 0.00
Synonyms: SK-MEL-5, SKMEL5
Caov-3: 0.00
Synonyms: Caov-3, CAOV3
HuP-T4: 0.00
Synonyms: HuP-T4, HUP-T4, HUPT4
NCI-H1755: 0.00
Synonyms: NCI-H1755, NCIH1755
VMRC-RCW: 0.00
Synonyms: VMRC-RCW, VMRCRCW
LoVo: 0.00
Synonyms: LoVo, LOVO
MDA-MB-435: 0.00
Synonyms: MDA-MB-435, MDA-MB-435S, MDAMB435S
A375: 0.00
Synonyms: A375, A-375
RMG-I: 0.00
Synonyms: RMG-I, RMGI
WM-793: 0.00
Synonyms: WM-793, WM793B, WM793
KYSE-70: 0.00
Synonyms: KYSE-70, KYSE70
LXF-289: 0.00
Synonyms: LXF-289, LXF289
NCI-H1435: 0.00
Synonyms: NCI-H1435, NCIH1435
NCI-H2023: 0.00
Synonyms: NCI-H2023, NCIH2023
NCI-H2126: 0.00
Synonyms: NCI-H2126, NCIH2126
NUGC-3: 0.00
Synonyms: NUGC-3, NUGC3
TCC-PAN2: 0.00
Synonyms: TCC-PAN2, TCCPAN2
YAPC: 0.00
Synonyms: YAPC
Download SVG
2.00
4.00
6.00
8.00
10.00
12.00
14.00
16.00
18.00
20.00
22.00
24.00
26.00
MCAS
MCAS
Calu-6
Calu-6
SR-786
SR-786
SW1573
SW1573
KMS-11
KMS-11
THP-1
THP-1
OAW-28
OAW-28
NCI-H2087
NCI-H2087
RH-30
RH-30
MOLP-2
MOLP-2
UM-UC-3
UM-UC-3
ECC10
ECC10
A2780
A2780
SW1116
SW1116
HPB-ALL
HPB-ALL
MM1-S
MM1-S
SNU-C5
SNU-C5
NOMO-1
NOMO-1
KMS-34
KMS-34
NU-DUL-1
NU-DUL-1
RCH-ACV
RCH-ACV
SW620
SW620
HCC1143
HCC1143
CW-2
CW-2
MOLM-16
MOLM-16
MOLM-6
MOLM-6
OCI-AML2
OCI-AML2
HUH-6-clone5
HUH-6-clone5
MCAS
Calu-6
SR-786
SW1573
KMS-11
THP-1
OAW-28
NCI-H2087
RH-30
MOLP-2
UM-UC-3
ECC10
A2780
SW1116
HPB-ALL
MM1-S
SNU-C5
NOMO-1
KMS-34
NU-DUL-1
RCH-ACV
SW620
HCC1143
CW-2
MOLM-16
MOLM-6
OCI-AML2
HUH-6-clone5
MCAS: 26.68 (log10 µM)
Synonyms: MCAS
Calu-6: 5.76 (log10 µM)
Synonyms: Calu-6, CALU6
SR-786: 2.38 (log10 µM)
Synonyms: SR-786, SR786
SW1573: 2.17 (log10 µM)
Synonyms: SW1573, SW 1573, SW_1573
KMS-11: 2.14 (log10 µM)
Synonyms: KMS-11, KMS11
THP-1: 1.85 (log10 µM)
Synonyms: THP-1, THP1
OAW-28: 1.82 (log10 µM)
Synonyms: OAW-28, OAW28
NCI-H2087: 1.82 (log10 µM)
Synonyms: NCI-H2087, NCIH2087
RH-30: 1.80 (log10 µM)
Synonyms: RH-30, RH30
MOLP-2: 1.76 (log10 µM)
Synonyms: MOLP-2, MOLP2
UM-UC-3: 1.76 (log10 µM)
Synonyms: UM-UC-3, UMUC3
ECC10: 1.75 (log10 µM)
Synonyms: ECC10
A2780: 1.73 (log10 µM)
Synonyms: A2780
SW1116: 1.72 (log10 µM)
Synonyms: SW1116, SW 1116
HPB-ALL: 1.72 (log10 µM)
Synonyms: HPB-ALL, HPBALL
MM1-S: 1.71 (log10 µM)
Synonyms: MM1-S, MM1S, MM.1S
SNU-C5: 1.65 (log10 µM)
Synonyms: SNU-C5, SNUC5
NOMO-1: 1.63 (log10 µM)
Synonyms: NOMO-1, NOMO1
KMS-34: 1.57 (log10 µM)
Synonyms: KMS-34, KMS34
NU-DUL-1: 1.54 (log10 µM)
Synonyms: NU-DUL-1, NUDUL1
RCH-ACV: 1.52 (log10 µM)
Synonyms: RCH-ACV, RCHACV
SW620: 1.51 (log10 µM)
Synonyms: SW620, SW 620
HCC1143: 1.45 (log10 µM)
Synonyms: HCC1143, hcc1143
CW-2: 1.42 (log10 µM)
Synonyms: CW-2, CW2
MOLM-16: 1.38 (log10 µM)
Synonyms: MOLM-16, MOLM16
MOLM-6: 1.34 (log10 µM)
Synonyms: MOLM-6, MOLM6
OCI-AML2: 1.27 (log10 µM)
Synonyms: OCI-AML2, OCIAML2
HUH-6-clone5: 1.18 (log10 µM)
Synonyms: HUH-6-clone5, HuH-6, HUH6
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
BRD-K09344309: AAC
AAC
Tissues
0.00
0.02
0.04
0.06
0.08
0.10
0.12
0.14
0.16
0.18
0.20
0.22
pleura
pleura
bone
bone
upper_aerodigestive_tract
upper_aerodigestive_tract
kidney
kidney
central_nervous_system
central_nervous_system
pancreas
pancreas
oesophagus
oesophagus
lung
lung
stomach
stomach
soft_tissue
soft_tissue
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
ovary
ovary
large_intestine
large_intestine
breast
breast
skin
skin
autonomic_ganglia
autonomic_ganglia
urinary_tract
urinary_tract
liver
liver
cervix
cervix
endometrium
endometrium
0.00
2.00
4.00
6.00
8.00
10.00
12.00
14.00
16.00
18.00
20.00
22.00
24.00
26.00
oesophagus
oesophagus
central_nervous_system
central_nervous_system
kidney
kidney
cervix
cervix
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
lung
lung
pleura
pleura
bone
bone
liver
liver
pancreas
pancreas
breast
breast
large_intestine
large_intestine
stomach
stomach
upper_aerodigestive_tract
upper_aerodigestive_tract
autonomic_ganglia
autonomic_ganglia
skin
skin
urinary_tract
urinary_tract
ovary
ovary
soft_tissue
soft_tissue
endometrium
endometrium
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to BRD-K09344309
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
COPE
CTRPv2
pan-cancer
AAC
-0.28
0.0007
mRNA
RGS18
CTRPv2
pan-cancer
AAC
0.26
0.0007
mRNA
SEPSECS
CTRPv2
pan-cancer
AAC
0.28
0.0007
mRNA
NEK3
CTRPv2
pan-cancer
AAC
0.27
0.0007
mRNA
ZNF668
CTRPv2
pan-cancer
AAC
-0.26
0.0007
mRNA
FAM122C
CTRPv2
pan-cancer
AAC
0.29
0.0007
mRNA
VAPA
CTRPv2
pan-cancer
AAC
0.28
0.0007
mRNA
CCR4
CTRPv2
pan-cancer
AAC
0.25
0.0008
mRNA
MFSD2B
CTRPv2
pan-cancer
AAC
0.25
0.0008
mRNA
PRUNE2
CTRPv2
pan-cancer
AAC
0.29
0.0008
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