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AT7867

AT7867

Synonyms

Sources	Names Used
CTRPv2	AT7867
PharmacoGx	AT7867

External IDs

Database	Identifier
Smiles:	Clc1ccc(cc1)C1(CCNCC1)c1ccc(cc1)-c1cn[nH]c1
Pubchem:	11175137

Annotated Targets

AKT2, GSK3B, PKIA, PRKACA, AKT1, AKT3, RPS6KB2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AT7867

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GLTSCR1L	CTRPv2	pan-cancer	AAC	0.14	0.0004
mRNA	CNPY4	CTRPv2	pan-cancer	AAC	0.14	0.0004
mRNA	CIC	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	NUDT3	CTRPv2	pan-cancer	AAC	0.14	0.0004
mRNA	RALGDS	CTRPv2	pan-cancer	AAC	0.14	0.0004
mRNA	HRH2	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	ARHGAP19-SLIT1	CTRPv2	pan-cancer	AAC	0.15	0.0004
mRNA	USP49	CTRPv2	pan-cancer	AAC	0.14	0.0004
mRNA	RBM5	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	MREG	CTRPv2	pan-cancer	AAC	-0.14	0.0005

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