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AT7867

AT7867

Synonyms

Sources	Names Used
CTRPv2	AT7867
PharmacoGx	AT7867

External IDs

Database	Identifier
Smiles:	Clc1ccc(cc1)C1(CCNCC1)c1ccc(cc1)-c1cn[nH]c1
Pubchem:	11175137

Annotated Targets

AKT2, GSK3B, PKIA, PRKACA, AKT1, AKT3, RPS6KB2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AT7867

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CDC40	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	KBTBD7	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	PXK	CTRPv2	pan-cancer	AAC	0.16	0.0002
mRNA	ARHGAP19	CTRPv2	pan-cancer	AAC	0.17	0.0002
mRNA	RP11-574K11.31	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	RNASEH2B	CTRPv2	pan-cancer	AAC	0.16	0.0002
mRNA	DCANP1	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	ZNF165	CTRPv2	pan-cancer	AAC	-0.15	0.0002
mRNA	PNRC1	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	CCAR1	CTRPv2	pan-cancer	AAC	0.14	0.0002

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