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barasertib

Synonyms

SourcesNames Used
CTRPv2barasertib
PharmacoGx barasertib

External IDs

DatabaseIdentifier
Smiles: CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1
Pubchem: 11497983

Annotated Targets

AURKA, AURKB

FDA Approval Status

Not Approved
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Top molecular features associated with response to barasertib


Feature TypeStandardized
Nominal ANOVA
mRNA LEF1 CTRPv2 pan-cancer AAC 0.19 1e-08
mRNA ANXA5 CTRPv2 pan-cancer AAC -0.25 1e-08
mRNA EIF3L CTRPv2 pan-cancer AAC 0.21 1e-08
mRNA LINGO3 CTRPv2 pan-cancer AAC 0.2 1e-08
mRNA NABP1 CTRPv2 pan-cancer AAC -0.18 1e-08
mRNA ZNF575 CTRPv2 pan-cancer AAC 0.19 1e-08
mRNA DOCK8 CTRPv2 pan-cancer AAC 0.25 1e-08
mRNA KDM2B CTRPv2 pan-cancer AAC 0.21 1e-08
mRNA HNRNPU CTRPv2 pan-cancer AAC 0.19 1e-08
mRNA MTG2 CTRPv2 pan-cancer AAC -0.18 1e-08
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