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BMS-345541

BMS-345541

Synonyms

Sources	Names Used
GDSC1000	BMS345541
CTRPv2	BMS-345541
PharmacoGx	BMS-345541

External IDs

Database	Identifier
Smiles:	Cc1cnc2c(NCCN)nc3ccc(C)cc3n12
Pubchem:	9926054

Annotated Targets

CHUK, IKBKB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BMS-345541

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ITK	GDSC1000	pan-cancer	AAC	0.2	3e-09
mRNA	CCDC138	GDSC1000	pan-cancer	AAC	0.19	3e-09
mRNA	PDIK1L	GDSC1000	pan-cancer	AAC	0.21	4e-09
mRNA	NINL	GDSC1000	pan-cancer	AAC	0.2	4e-09
mRNA	ATOX1	GDSC1000	pan-cancer	AAC	-0.2	4e-09
mRNA	ZNF445	GDSC1000	pan-cancer	AAC	0.21	5e-09
mRNA	CD7	GDSC1000	pan-cancer	AAC	0.18	5e-09
mRNA	ARID1A	GDSC1000	pan-cancer	AAC	0.2	6e-09
mRNA	HLA-DPA1	GDSC1000	pan-cancer	AAC	-0.22	8e-09
mRNA	NOTCH1	GDSC1000	pan-cancer	AAC	0.18	8e-09

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