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BMS-345541

BMS-345541

Synonyms

Sources	Names Used
GDSC1000	BMS345541
CTRPv2	BMS-345541
PharmacoGx	BMS-345541

External IDs

Database	Identifier
Smiles:	Cc1cnc2c(NCCN)nc3ccc(C)cc3n12
Pubchem:	9926054

Annotated Targets

CHUK, IKBKB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BMS-345541

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CD3G	GDSC1000	pan-cancer	AAC	0.25	2e-16
mRNA	CD3E	GDSC1000	pan-cancer	AAC	0.24	2e-14
mRNA	GIMAP6	GDSC1000	pan-cancer	AAC	0.24	9e-14
mRNA	CD247	GDSC1000	pan-cancer	AAC	0.24	2e-13
mRNA	BCL11B	GDSC1000	pan-cancer	AAC	0.23	6e-13
mRNA	TNRC6C	GDSC1000	pan-cancer	AAC	0.24	7e-13
mRNA	SLA	GDSC1000	pan-cancer	AAC	0.25	7e-12
mRNA	CD1A	GDSC1000	pan-cancer	AAC	0.21	2e-11
mRNA	CD3D	GDSC1000	pan-cancer	AAC	0.22	3e-11
mRNA	OGN	GDSC1000	pan-cancer	AAC	0.2	3e-11

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