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BMS-345541

BMS-345541

Synonyms

Sources	Names Used
GDSC1000	BMS345541
CTRPv2	BMS-345541
PharmacoGx	BMS-345541

External IDs

Database	Identifier
Smiles:	Cc1cnc2c(NCCN)nc3ccc(C)cc3n12
Pubchem:	9926054

Annotated Targets

CHUK, IKBKB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BMS-345541

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KHDRBS1	GDSC1000	pan-cancer	AAC	0.19	3e-08
mRNA	ARID2	GDSC1000	pan-cancer	AAC	0.18	3e-08
mRNA	PAWR	GDSC1000	pan-cancer	AAC	-0.2	3e-08
mRNA	ATAD5	GDSC1000	pan-cancer	AAC	0.19	3e-08
mRNA	RNF219	GDSC1000	pan-cancer	AAC	0.18	4e-08
mRNA	CCAR1	GDSC1000	pan-cancer	AAC	0.19	4e-08
mRNA	CTSZ	GDSC1000	pan-cancer	AAC	-0.18	4e-08
mRNA	CCDC66	GDSC1000	pan-cancer	AAC	0.19	5e-08
mRNA	MATK	GDSC1000	pan-cancer	AAC	0.17	5e-08
mRNA	ECI1	GDSC1000	pan-cancer	AAC	-0.18	5e-08

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