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BMS-345541

BMS-345541

Synonyms

Sources	Names Used
GDSC1000	BMS345541
CTRPv2	BMS-345541
PharmacoGx	BMS-345541

External IDs

Database	Identifier
Smiles:	Cc1cnc2c(NCCN)nc3ccc(C)cc3n12
Pubchem:	9926054

Annotated Targets

CHUK, IKBKB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BMS-345541

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DOT1L	CTRPv2	pan-cancer	AAC	0.15	0.001
mRNA	HIF1A	CTRPv2	pan-cancer	AAC	-0.13	0.001
mRNA	ESPL1	GDSC1000	pan-cancer	AAC	0.11	0.001
mRNA	HESX1	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	C17orf80	GDSC1000	pan-cancer	AAC	0.11	0.001
mRNA	MTERF3	GDSC1000	pan-cancer	AAC	0.1	0.001
mRNA	RPL14	CTRPv2	pan-cancer	AAC	0.13	0.001
mRNA	WWOX	GDSC1000	pan-cancer	AAC	0.1	0.001
mRNA	IQGAP2	GDSC1000	pan-cancer	AAC	0.11	0.001
mRNA	BLMH	GDSC1000	pan-cancer	AAC	0.11	0.001

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