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BMS-345541

BMS-345541

Synonyms

Sources	Names Used
GDSC1000	BMS345541
CTRPv2	BMS-345541
PharmacoGx	BMS-345541

External IDs

Database	Identifier
Smiles:	Cc1cnc2c(NCCN)nc3ccc(C)cc3n12
Pubchem:	9926054

Annotated Targets

CHUK, IKBKB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BMS-345541

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HNRNPDL	GDSC1000	pan-cancer	AAC	0.17	6e-07
mRNA	FAM117B	GDSC1000	pan-cancer	AAC	0.16	6e-07
mRNA	LIN28B	GDSC1000	pan-cancer	AAC	0.17	6e-07
mRNA	GTF3C5	GDSC1000	pan-cancer	AAC	0.16	6e-07
mRNA	SREBF2	CTRPv2	pan-cancer	AAC	0.19	7e-07
mRNA	PON2	GDSC1000	pan-cancer	AAC	-0.2	7e-07
mRNA	CXorf65	GDSC1000	pan-cancer	AAC	0.2	7e-07
mRNA	ALMS1	GDSC1000	pan-cancer	AAC	0.16	7e-07
mRNA	HNRNPR	GDSC1000	pan-cancer	AAC	0.16	7e-07
mRNA	HIST1H3F	GDSC1000	pan-cancer	AAC	0.17	7e-07

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