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BMS-345541

BMS-345541

Synonyms

Sources	Names Used
GDSC1000	BMS345541
CTRPv2	BMS-345541
PharmacoGx	BMS-345541

External IDs

Database	Identifier
Smiles:	Cc1cnc2c(NCCN)nc3ccc(C)cc3n12
Pubchem:	9926054

Annotated Targets

CHUK, IKBKB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BMS-345541

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FRAT2	CTRPv2	pan-cancer	AAC	0.2	4e-07
mRNA	BCOR	GDSC1000	pan-cancer	AAC	0.17	5e-07
mRNA	EVL	GDSC1000	pan-cancer	AAC	0.18	5e-07
mRNA	PRKCQ	GDSC1000	pan-cancer	AAC	0.17	5e-07
mRNA	PLPP3	GDSC1000	pan-cancer	AAC	-0.16	5e-07
mRNA	FYB	GDSC1000	pan-cancer	AAC	0.17	5e-07
mRNA	SLC39A13	CTRPv2	pan-cancer	AAC	-0.22	5e-07
mRNA	MEX3A	GDSC1000	pan-cancer	AAC	0.18	5e-07
mRNA	CFAP47	CTRPv2	pan-cancer	AAC	0.18	5e-07
mRNA	NEK6	GDSC1000	pan-cancer	AAC	-0.17	6e-07

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