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tandutinib

tandutinib

Synonyms

Sources	Names Used
CTRPv2	tandutinib
PharmacoGx	tandutinib

External IDs

Database	Identifier
Smiles:	COc1cc2c(ncnc2cc1OCCCN3CCCCC3)N4CCN(CC4)C(=O)Nc5ccc(OC(C)C)cc5
Pubchem:	3038522

Annotated Targets

KIT, CSF1R, FLT3, PDGFD, PDGFRB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to tandutinib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TNPO2	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	CASP8AP2	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	PXK	CTRPv2	pan-cancer	AAC	0.17	0.0001
mRNA	CITED2	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	PRRX1	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	TP53RK	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	COL6A3	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	ZNF397	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	HEBP2	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	RAB3D	CTRPv2	pan-cancer	AAC	0.15	0.0001

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