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tandutinib

tandutinib

Synonyms

Sources	Names Used
CTRPv2	tandutinib
PharmacoGx	tandutinib

External IDs

Database	Identifier
Smiles:	COc1cc2c(ncnc2cc1OCCCN3CCCCC3)N4CCN(CC4)C(=O)Nc5ccc(OC(C)C)cc5
Pubchem:	3038522

Annotated Targets

KIT, CSF1R, FLT3, PDGFD, PDGFRB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to tandutinib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RMI1	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	REV3L	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	ZNF286B	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	CTC-398G3.6	CTRPv2	pan-cancer	AAC	0.14	0.002
mRNA	STARD5	CTRPv2	pan-cancer	AAC	-0.13	0.002
mRNA	ALDH8A1	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	GNB4	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	KCNK10	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	ADGRA2	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	ZNF561	CTRPv2	pan-cancer	AAC	0.11	0.002

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