About
Documentation
Cite Us!
Github
Download
News
Explore
Batch Query
Search
Site
Home
About
Documentation
PharmacoGx
Cite Us!
Tools
Explore
Batch Query
Search
GitHub
Datatypes
datasets
cell lines
tissues
drugs
genes
experiments
Home
/
Compounds
/
crizotinib:PLX-4032 (2:1 mol/mol)
crizotinib:PLX-4032 (2:1 mol/mol)
Synonyms
Sources
Names Used
CTRPv2
crizotinib:PLX-4032 (2:1 mol/mol)
PharmacoGx
crizotinib:PLX-4032 (2:1 mol/mol)
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with
crizotinib:PLX-4032 (2:1 mol/mol) (per
dataset)
0
100
200
300
400
500
600
700
800
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
824
Download SVG
Number of tissues tested with
crizotinib:PLX-4032 (2:1 mol/mol) (per
dataset)
0
2
4
6
8
10
12
14
16
18
20
22
24
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
25
Download SVG
Dataset Select
all
CTRPv2
crizotinib:PLX-4032 (2:1 mol/mol): AAC
AAC
0.00
0.10
0.20
0.30
0.40
0.50
0.60
0.70
SNU-5
SNU-5
SNU-620
SNU-620
SW948
SW948
SUP-M2
SUP-M2
EBC-1
EBC-1
IM-95
IM-95
Ki-JK
Ki-JK
Hs 746T
Hs 746T
SU-DHL-1
SU-DHL-1
DEL
DEL
ASKA
ASKA
SNU-81
SNU-81
KU812
KU812
SIG-M5
SIG-M5
WM-88
WM-88
ALL-SIL
ALL-SIL
DU-4475
DU-4475
JK-1
JK-1
JURL-MK1
JURL-MK1
NCI-H1573
NCI-H1573
YAMATO
YAMATO
NCO2
NCO2
NB1
NB1
MHH-NB-11
MHH-NB-11
MOLP-8
MOLP-8
WM-983B
WM-983B
SH-4
SH-4
TM87-16
TM87-16
A4-Fuk
A4-Fuk
MOLM-16
MOLM-16
PSTS
PSTS
OVSAHO
OVSAHO
KLE
KLE
TCC-PAN2
TCC-PAN2
NCI-H2126
NCI-H2126
BEN
BEN
KURAMOCHI
KURAMOCHI
NCI-H1435
NCI-H1435
KMM-1
KMM-1
G-361
G-361
TUHR14TKB
TUHR14TKB
Ishikawa (Heraklio) 02 ER-
Ishikawa (Heraklio) 02 ER-
HCC202
HCC202
SNU-398
SNU-398
MDA-MB-361
MDA-MB-361
EFO-27
EFO-27
CAKI-1
CAKI-1
BT-474
BT-474
KNS-62
KNS-62
REC-1
REC-1
NUGC-3
NUGC-3
SNU-C4
SNU-C4
NCI-H226
NCI-H226
FTC-133
FTC-133
JHH-6
JHH-6
KARPAS-620
KARPAS-620
HCC1419
HCC1419
Panc 05.04
Panc 05.04
KYSE-70
KYSE-70
NCI-H2023
NCI-H2023
SNU-5
SNU-620
SW948
SUP-M2
EBC-1
IM-95
Ki-JK
Hs 746T
SU-DHL-1
DEL
ASKA
SNU-81
KU812
SIG-M5
WM-88
ALL-SIL
DU-4475
JK-1
JURL-MK1
NCI-H1573
YAMATO
NCO2
NB1
MHH-NB-11
MOLP-8
WM-983B
SH-4
TM87-16
A4-Fuk
MOLM-16
PSTS
OVSAHO
KLE
TCC-PAN2
NCI-H2126
BEN
KURAMOCHI
NCI-H1435
KMM-1
G-361
TUHR14TKB
Ishikawa (Heraklio) 02 ER-
HCC202
SNU-398
MDA-MB-361
EFO-27
CAKI-1
BT-474
KNS-62
REC-1
NUGC-3
SNU-C4
NCI-H226
FTC-133
JHH-6
KARPAS-620
HCC1419
Panc 05.04
KYSE-70
NCI-H2023
SNU-5: 0.77
Synonyms: SNU-5, SNU5
SNU-620: 0.70
Synonyms: SNU-620, SNU620
SW948: 0.61
Synonyms: SW948, SW 948
SUP-M2: 0.61
Synonyms: SUP-M2, SUPM2
EBC-1: 0.58
Synonyms: EBC-1, EBC1
IM-95: 0.57
Synonyms: IM-95, IM95
Ki-JK: 0.56
Synonyms: Ki-JK, KIJK
Hs 746T: 0.56
Synonyms: Hs 746T, Hs_746T, Hs746T, HS746T
SU-DHL-1: 0.51
Synonyms: SU-DHL-1, SUDHL1
DEL: 0.51
Synonyms: DEL
ASKA: 0.49
Synonyms: ASKA
SNU-81: 0.47
Synonyms: SNU-81, SNU81
KU812: 0.47
Synonyms: KU812
SIG-M5: 0.47
Synonyms: SIG-M5, SIGM5
WM-88: 0.46
Synonyms: WM-88, WM88
ALL-SIL: 0.46
Synonyms: ALL-SIL, ALLSIL
DU-4475: 0.46
Synonyms: DU-4475, DU4475, du4475
JK-1: 0.45
Synonyms: JK-1, JK1
JURL-MK1: 0.45
Synonyms: JURL-MK1, JURLMK1
NCI-H1573: 0.43
Synonyms: NCI-H1573, NCIH1573
YAMATO: 0.43
Synonyms: YAMATO
NCO2: 0.42
Synonyms: NCO2
NB1: 0.42
Synonyms: NB1, NB-1
MHH-NB-11: 0.41
Synonyms: MHH-NB-11, MHHNB11
MOLP-8: 0.40
Synonyms: MOLP-8, MOLP8
WM-983B: 0.40
Synonyms: WM-983B, WM983B
SH-4: 0.39
Synonyms: SH-4, SH4
TM87-16: 0.39
Synonyms: TM87-16
A4-Fuk: 0.39
Synonyms: A4-Fuk, A4/Fuk, A4_Fuk, A4FUK
MOLM-16: 0.39
Synonyms: MOLM-16, MOLM16
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
PSTS: 0.08
Synonyms: PSTS
OVSAHO: 0.08
Synonyms: OVSAHO
KLE: 0.08
Synonyms: KLE
TCC-PAN2: 0.07
Synonyms: TCC-PAN2, TCCPAN2
NCI-H2126: 0.07
Synonyms: NCI-H2126, NCIH2126
BEN: 0.07
Synonyms: BEN
KURAMOCHI: 0.07
Synonyms: KURAMOCHI
NCI-H1435: 0.07
Synonyms: NCI-H1435, NCIH1435
KMM-1: 0.07
Synonyms: KMM-1, KMM1
G-361: 0.07
Synonyms: G-361, G361
TUHR14TKB: 0.06
Synonyms: TUHR14TKB
Ishikawa (Heraklio) 02 ER-: 0.06
Synonyms: Ishikawa (Heraklio) 02 ER-, Ishikawa__Heraklio__02_ER-, Ishikawa_Heraklio_02ER-, ISHIKAWAHERAKLIO02ER
HCC202: 0.06
Synonyms: HCC202, hcc202
SNU-398: 0.06
Synonyms: SNU-398, SNU398
MDA-MB-361: 0.06
Synonyms: MDA-MB-361, MDAMB361, mdamb361
EFO-27: 0.06
Synonyms: EFO-27, EFO27
CAKI-1: 0.05
Synonyms: CAKI-1, Caki-1, CAKI1
BT-474: 0.05
Synonyms: BT-474, BT474, bt474
KNS-62: 0.05
Synonyms: KNS-62, KNS62
REC-1: 0.05
Synonyms: REC-1, REC1
NUGC-3: 0.04
Synonyms: NUGC-3, NUGC3
SNU-C4: 0.04
Synonyms: SNU-C4, SNUC4
NCI-H226: 0.04
Synonyms: NCI-H226, NCIH226
FTC-133: 0.04
Synonyms: FTC-133, FTC133
JHH-6: 0.04
Synonyms: JHH-6, JHH6
KARPAS-620: 0.03
Synonyms: KARPAS-620, KARPAS620
HCC1419: 0.02
Synonyms: HCC1419, hcc1419
Panc 05.04: 0.02
Synonyms: Panc 05.04, Panc_05.04, PANC0504
KYSE-70: 0.02
Synonyms: KYSE-70, KYSE70
NCI-H2023: 0.01
Synonyms: NCI-H2023, NCIH2023
Download SVG
-1.50
-1.00
-0.50
0.00
0.50
1.00
1.50
2.00
2.50
P3HR-1
P3HR-1
MKN45
MKN45
BICR 56
BICR 56
NCI-H226
NCI-H226
HCC1419
HCC1419
JHH-6
JHH-6
FTC-133
FTC-133
REC-1
REC-1
SNU-C4
SNU-C4
KNS-62
KNS-62
SW1783
SW1783
BT-474
BT-474
KMM-1
KMM-1
CAKI-1
CAKI-1
TUHR14TKB
TUHR14TKB
EFO-27
EFO-27
MDA-MB-361
MDA-MB-361
Ishikawa (Heraklio) 02 ER-
Ishikawa (Heraklio) 02 ER-
SNU-398
SNU-398
HCC202
HCC202
ZR-75-30
ZR-75-30
KURAMOCHI
KURAMOCHI
Hs 839.T
Hs 839.T
PSTS
PSTS
KLE
KLE
BEN
BEN
MFE-319
MFE-319
OVSAHO
OVSAHO
BT179
BT179
SW620
SW620
CML-T1
CML-T1
MOLP-8
MOLP-8
WM-115
WM-115
WM-983B
WM-983B
MOLM-16
MOLM-16
SH-4
SH-4
TM87-16
TM87-16
A4-Fuk
A4-Fuk
EM-2
EM-2
MHH-NB-11
MHH-NB-11
NB1
NB1
YAMATO
YAMATO
NCO2
NCO2
JURL-MK1
JURL-MK1
DU-4475
DU-4475
SNU-81
SNU-81
ALL-SIL
ALL-SIL
JK-1
JK-1
SIG-M5
SIG-M5
KU812
KU812
WM-88
WM-88
ASKA
ASKA
DEL
DEL
SU-DHL-1
SU-DHL-1
Ki-JK
Ki-JK
Hs 746T
Hs 746T
IM-95
IM-95
SUP-M2
SUP-M2
EBC-1
EBC-1
SNU-620
SNU-620
P3HR-1
MKN45
BICR 56
NCI-H226
HCC1419
JHH-6
FTC-133
REC-1
SNU-C4
KNS-62
SW1783
BT-474
KMM-1
CAKI-1
TUHR14TKB
EFO-27
MDA-MB-361
Ishikawa (Heraklio) 02 ER-
SNU-398
HCC202
ZR-75-30
KURAMOCHI
Hs 839.T
PSTS
KLE
BEN
MFE-319
OVSAHO
BT179
SW620
CML-T1
MOLP-8
WM-115
WM-983B
MOLM-16
SH-4
TM87-16
A4-Fuk
EM-2
MHH-NB-11
NB1
YAMATO
NCO2
JURL-MK1
DU-4475
SNU-81
ALL-SIL
JK-1
SIG-M5
KU812
WM-88
ASKA
DEL
SU-DHL-1
Ki-JK
Hs 746T
IM-95
SUP-M2
EBC-1
SNU-620
P3HR-1: 2.50 (log10 µM)
Synonyms: P3HR-1, P3HR1
MKN45: 1.79 (log10 µM)
Synonyms: MKN45, MKN-45
BICR 56: 1.76 (log10 µM)
Synonyms: BICR 56, BICR_56, BICR56
NCI-H226: 1.75 (log10 µM)
Synonyms: NCI-H226, NCIH226
HCC1419: 1.65 (log10 µM)
Synonyms: HCC1419, hcc1419
JHH-6: 1.56 (log10 µM)
Synonyms: JHH-6, JHH6
FTC-133: 1.56 (log10 µM)
Synonyms: FTC-133, FTC133
REC-1: 1.52 (log10 µM)
Synonyms: REC-1, REC1
SNU-C4: 1.52 (log10 µM)
Synonyms: SNU-C4, SNUC4
KNS-62: 1.49 (log10 µM)
Synonyms: KNS-62, KNS62
SW1783: 1.49 (log10 µM)
Synonyms: SW1783, SW 1783, SW_1783
BT-474: 1.48 (log10 µM)
Synonyms: BT-474, BT474, bt474
KMM-1: 1.48 (log10 µM)
Synonyms: KMM-1, KMM1
CAKI-1: 1.47 (log10 µM)
Synonyms: CAKI-1, Caki-1, CAKI1
TUHR14TKB: 1.46 (log10 µM)
Synonyms: TUHR14TKB
EFO-27: 1.46 (log10 µM)
Synonyms: EFO-27, EFO27
MDA-MB-361: 1.46 (log10 µM)
Synonyms: MDA-MB-361, MDAMB361, mdamb361
Ishikawa (Heraklio) 02 ER-: 1.45 (log10 µM)
Synonyms: Ishikawa (Heraklio) 02 ER-, Ishikawa__Heraklio__02_ER-, Ishikawa_Heraklio_02ER-, ISHIKAWAHERAKLIO02ER
SNU-398: 1.44 (log10 µM)
Synonyms: SNU-398, SNU398
HCC202: 1.44 (log10 µM)
Synonyms: HCC202, hcc202
ZR-75-30: 1.41 (log10 µM)
Synonyms: ZR-75-30, ZR7530, zr7530
KURAMOCHI: 1.40 (log10 µM)
Synonyms: KURAMOCHI
Hs 839.T: 1.40 (log10 µM)
Synonyms: Hs 839.T, Hs_839.T, HS839T
PSTS: 1.39 (log10 µM)
Synonyms: PSTS
KLE: 1.39 (log10 µM)
Synonyms: KLE
BEN: 1.39 (log10 µM)
Synonyms: BEN
MFE-319: 1.37 (log10 µM)
Synonyms: MFE-319, MFE319
OVSAHO: 1.36 (log10 µM)
Synonyms: OVSAHO
BT179: 1.35 (log10 µM)
Synonyms: BT179
SW620: 1.35 (log10 µM)
Synonyms: SW620, SW 620
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
CML-T1: -0.01 (log10 µM)
Synonyms: CML-T1, CMLT1
MOLP-8: -0.01 (log10 µM)
Synonyms: MOLP-8, MOLP8
WM-115: -0.02 (log10 µM)
Synonyms: WM-115, WM115
WM-983B: -0.04 (log10 µM)
Synonyms: WM-983B, WM983B
MOLM-16: -0.04 (log10 µM)
Synonyms: MOLM-16, MOLM16
SH-4: -0.04 (log10 µM)
Synonyms: SH-4, SH4
TM87-16: -0.06 (log10 µM)
Synonyms: TM87-16
A4-Fuk: -0.06 (log10 µM)
Synonyms: A4-Fuk, A4/Fuk, A4_Fuk, A4FUK
EM-2: -0.15 (log10 µM)
Synonyms: EM-2, EM2
MHH-NB-11: -0.16 (log10 µM)
Synonyms: MHH-NB-11, MHHNB11
NB1: -0.20 (log10 µM)
Synonyms: NB1, NB-1
YAMATO: -0.20 (log10 µM)
Synonyms: YAMATO
NCO2: -0.27 (log10 µM)
Synonyms: NCO2
JURL-MK1: -0.33 (log10 µM)
Synonyms: JURL-MK1, JURLMK1
DU-4475: -0.36 (log10 µM)
Synonyms: DU-4475, DU4475, du4475
SNU-81: -0.37 (log10 µM)
Synonyms: SNU-81, SNU81
ALL-SIL: -0.38 (log10 µM)
Synonyms: ALL-SIL, ALLSIL
JK-1: -0.38 (log10 µM)
Synonyms: JK-1, JK1
SIG-M5: -0.49 (log10 µM)
Synonyms: SIG-M5, SIGM5
KU812: -0.49 (log10 µM)
Synonyms: KU812
WM-88: -0.52 (log10 µM)
Synonyms: WM-88, WM88
ASKA: -0.62 (log10 µM)
Synonyms: ASKA
DEL: -0.62 (log10 µM)
Synonyms: DEL
SU-DHL-1: -0.66 (log10 µM)
Synonyms: SU-DHL-1, SUDHL1
Ki-JK: -0.85 (log10 µM)
Synonyms: Ki-JK, KIJK
Hs 746T: -0.94 (log10 µM)
Synonyms: Hs 746T, Hs_746T, Hs746T, HS746T
IM-95: -1.00 (log10 µM)
Synonyms: IM-95, IM95
SUP-M2: -1.05 (log10 µM)
Synonyms: SUP-M2, SUPM2
EBC-1: -1.13 (log10 µM)
Synonyms: EBC-1, EBC1
SNU-620: -1.53 (log10 µM)
Synonyms: SNU-620, SNU620
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
crizotinib:PLX-4032 (2:1 mol/mol): AAC
AAC
Tissues
0.10
0.20
0.30
0.40
0.50
0.60
0.70
breast
breast
ovary
ovary
oesophagus
oesophagus
endometrium
endometrium
kidney
kidney
prostate
prostate
pancreas
pancreas
stomach
stomach
biliary_tract
biliary_tract
pleura
pleura
urinary_tract
urinary_tract
unknown
unknown
central_nervous_system
central_nervous_system
lung
lung
bone
bone
upper_aerodigestive_tract
upper_aerodigestive_tract
liver
liver
large_intestine
large_intestine
thyroid
thyroid
cervix
cervix
soft_tissue
soft_tissue
salivary_gland
salivary_gland
skin
skin
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
autonomic_ganglia
autonomic_ganglia
-2.00
-1.50
-1.00
-0.50
0.00
0.50
1.00
1.50
cervix
cervix
autonomic_ganglia
autonomic_ganglia
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
skin
skin
soft_tissue
soft_tissue
thyroid
thyroid
salivary_gland
salivary_gland
large_intestine
large_intestine
bone
bone
upper_aerodigestive_tract
upper_aerodigestive_tract
lung
lung
liver
liver
central_nervous_system
central_nervous_system
pleura
pleura
unknown
unknown
urinary_tract
urinary_tract
biliary_tract
biliary_tract
pancreas
pancreas
kidney
kidney
stomach
stomach
prostate
prostate
oesophagus
oesophagus
endometrium
endometrium
ovary
ovary
breast
breast
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to crizotinib:PLX-4032 (2:1 mol/mol)
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
DNAJC14
CTRPv2
pan-cancer
AAC
-0.08
0.02
mRNA
LINC01314
CTRPv2
pan-cancer
AAC
0.086
0.02
mRNA
ITIH6
CTRPv2
pan-cancer
AAC
0.082
0.02
mRNA
CEACAM21
CTRPv2
pan-cancer
AAC
-0.085
0.02
mRNA
SLC25A43
CTRPv2
pan-cancer
AAC
-0.082
0.02
mRNA
CTB-102L5.4
CTRPv2
pan-cancer
AAC
-0.094
0.02
mRNA
RNH1
CTRPv2
pan-cancer
AAC
-0.082
0.02
mRNA
PDLIM2
CTRPv2
pan-cancer
AAC
-0.08
0.02
mRNA
RETN
CTRPv2
pan-cancer
AAC
0.077
0.02
mRNA
TYW5
CTRPv2
pan-cancer
AAC
0.079
0.02
← Previous
1
2
…
189
190
191
…
199
200
Next →
Download CSV