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BRD-K58730230
BRD-K58730230
Synonyms
Sources
Names Used
CTRPv2
BRD-K58730230
PharmacoGx
BRD-K58730230
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with
BRD-K58730230 (per dataset)
0
20
40
60
80
100
120
140
160
180
200
220
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
225
Download SVG
Number of tissues tested with
BRD-K58730230 (per dataset)
0
2
4
6
8
10
12
14
16
18
20
22
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
22
Download SVG
Dataset Select
all
CTRPv2
BRD-K58730230: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
HCC1569
HCC1569
BEN
BEN
CAL-12T
CAL-12T
DLD-1
DLD-1
HCT-116
HCT-116
SNU-308
SNU-308
KU-19-19
KU-19-19
HT-29
HT-29
SW48
SW48
U-2-OS
U-2-OS
CAS-1
CAS-1
NCI-H727
NCI-H727
HCC-78
HCC-78
MOR/CPR
MOR/CPR
KLE
KLE
Ishikawa (Heraklio) 02 ER-
Ishikawa (Heraklio) 02 ER-
ONS-76
ONS-76
HEC-265
HEC-265
253J
253J
SNU-213
SNU-213
8505C
8505C
MKN45
MKN45
BHT-101
BHT-101
NCI-N87
NCI-N87
MV-4-11
MV-4-11
KMS-26
KMS-26
SNU-46
SNU-46
KPL-1
KPL-1
LCLC-103H
LCLC-103H
NCI-H2291
NCI-H2291
KP-4
KP-4
COLO-699
COLO-699
SHP-77
SHP-77
SNU-1196
SNU-1196
SNU-5
SNU-5
HCC-95
HCC-95
KE-37
KE-37
RPMI-7951
RPMI-7951
KCL-22
KCL-22
HEC-6
HEC-6
NCI-H211
NCI-H211
SNU-201
SNU-201
253J-BV
253J-BV
BFTC-909
BFTC-909
HuCCT1
HuCCT1
KMRC-20
KMRC-20
NCI-H2009
NCI-H2009
COLO-741
COLO-741
NCI-H1155
NCI-H1155
HCC-366
HCC-366
OVTOKO
OVTOKO
Hep 3B2.1-7
Hep 3B2.1-7
HSC-3
HSC-3
U-87-MG
U-87-MG
KP-3
KP-3
HCC-2108
HCC-2108
JURKAT
JURKAT
KM-H2
KM-H2
LAMA-84
LAMA-84
CAL-148
CAL-148
HCC1569
BEN
CAL-12T
DLD-1
HCT-116
SNU-308
KU-19-19
HT-29
SW48
U-2-OS
CAS-1
NCI-H727
HCC-78
MOR/CPR
KLE
Ishikawa (Heraklio) 02 ER-
ONS-76
HEC-265
253J
SNU-213
8505C
MKN45
BHT-101
NCI-N87
MV-4-11
KMS-26
SNU-46
KPL-1
LCLC-103H
NCI-H2291
KP-4
COLO-699
SHP-77
SNU-1196
SNU-5
HCC-95
KE-37
RPMI-7951
KCL-22
HEC-6
NCI-H211
SNU-201
253J-BV
BFTC-909
HuCCT1
KMRC-20
NCI-H2009
COLO-741
NCI-H1155
HCC-366
OVTOKO
Hep 3B2.1-7
HSC-3
U-87-MG
KP-3
HCC-2108
JURKAT
KM-H2
LAMA-84
CAL-148
HCC1569: 0.29
Synonyms: HCC1569, hcc1569
BEN: 0.24
Synonyms: BEN
CAL-12T: 0.16
Synonyms: CAL-12T, CAL12T
DLD-1: 0.16
Synonyms: DLD-1, DLD1
HCT-116: 0.14
Synonyms: HCT-116, HCT 116, HCT_116, HCT116
SNU-308: 0.14
Synonyms: SNU-308, SNU308
KU-19-19: 0.12
Synonyms: KU-19-19, KU1919
HT-29: 0.12
Synonyms: HT-29, HT29
SW48: 0.12
Synonyms: SW48, SW 48
U-2-OS: 0.11
Synonyms: U-2-OS, U-2 OS, U-2_OS, U2OS
CAS-1: 0.11
Synonyms: CAS-1, CAS1
NCI-H727: 0.10
Synonyms: NCI-H727, NCIH727
HCC-78: 0.10
Synonyms: HCC-78, HCC78
MOR/CPR: 0.10
Synonyms: MOR/CPR, MOR_CPR, MORCPR
KLE: 0.09
Synonyms: KLE
Ishikawa (Heraklio) 02 ER-: 0.09
Synonyms: Ishikawa (Heraklio) 02 ER-, Ishikawa__Heraklio__02_ER-, Ishikawa_Heraklio_02ER-, ISHIKAWAHERAKLIO02ER
ONS-76: 0.09
Synonyms: ONS-76, ONS76
HEC-265: 0.08
Synonyms: HEC-265, HEC265
253J: 0.08
Synonyms: 253J
SNU-213: 0.07
Synonyms: SNU-213, SNU213
8505C: 0.07
Synonyms: 8505C
MKN45: 0.07
Synonyms: MKN45, MKN-45
BHT-101: 0.07
Synonyms: BHT-101, BHT101
NCI-N87: 0.07
Synonyms: NCI-N87, NCIN87
MV-4-11: 0.07
Synonyms: MV-4-11, MV411
KMS-26: 0.07
Synonyms: KMS-26, KMS26
SNU-46: 0.07
Synonyms: SNU-46, SNU46
KPL-1: 0.07
Synonyms: KPL-1, KPL1, kpl1
LCLC-103H: 0.07
Synonyms: LCLC-103H, LCLC103H
NCI-H2291: 0.07
Synonyms: NCI-H2291, NCIH2291
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
KP-4: 0.00
Synonyms: KP-4, KP4
COLO-699: 0.00
Synonyms: COLO-699, COLO 699, COLO699
SHP-77: 0.00
Synonyms: SHP-77, SHP77
SNU-1196: 0.00
Synonyms: SNU-1196, SNU1196
SNU-5: 0.00
Synonyms: SNU-5, SNU5
HCC-95: 0.00
Synonyms: HCC-95, HCC95
KE-37: 0.00
Synonyms: KE-37, KE37
RPMI-7951: 0.00
Synonyms: RPMI-7951, RPMI7951
KCL-22: 0.00
Synonyms: KCL-22, KCL22
HEC-6: 0.00
Synonyms: HEC-6, HEC6
NCI-H211: 0.00
Synonyms: NCI-H211, NCIH211
SNU-201: 0.00
Synonyms: SNU-201, SNU201
253J-BV: 0.00
Synonyms: 253J-BV, 253JBV
BFTC-909: 0.00
Synonyms: BFTC-909, BFTC909
HuCCT1: 0.00
Synonyms: HuCCT1, HUCCT1
KMRC-20: 0.00
Synonyms: KMRC-20, KMRC20
NCI-H2009: 0.00
Synonyms: NCI-H2009, NCIH2009
COLO-741: 0.00
Synonyms: COLO-741, COLO 741, COLO_741, COLO741
NCI-H1155: 0.00
Synonyms: NCI-H1155, NCIH1155
HCC-366: 0.00
Synonyms: HCC-366, HCC366
OVTOKO: 0.00
Synonyms: OVTOKO
Hep 3B2.1-7: 0.00
Synonyms: Hep 3B2.1-7, Hep_3B2.1-7, Hep3B2-1-7, Hep 3B2_1-7, Hep_3B2_1-7, HEP3B217
HSC-3: 0.00
Synonyms: HSC-3, HSC3
U-87-MG: 0.00
Synonyms: U-87-MG, U-87 MG, U-87_MG, U87MG
KP-3: 0.00
Synonyms: KP-3, KP3
HCC-2108: 0.00
Synonyms: HCC-2108, HCC2108
JURKAT: 0.00
Synonyms: JURKAT, Jurkat
KM-H2: 0.00
Synonyms: KM-H2, KMH2
LAMA-84: 0.00
Synonyms: LAMA-84, LAMA84
CAL-148: 0.00
Synonyms: CAL-148, CAL148, cal148
Download SVG
2.00
4.00
6.00
8.00
10.00
12.00
14.00
NCI-H1299
NCI-H1299
SBC-5
SBC-5
U-2-OS
U-2-OS
MEL-HO
MEL-HO
SNU-1041
SNU-1041
JIMT-1
JIMT-1
NCI-H292
NCI-H292
COLO-205
COLO-205
EHEB
EHEB
KMS-27
KMS-27
SNU-1076
SNU-1076
NCI-N87
NCI-N87
VM-CUB-1
VM-CUB-1
RL95-2
RL95-2
PEER
PEER
KMM-1
KMM-1
RPMI-8402
RPMI-8402
KE-37
KE-37
SNU-1196
SNU-1196
CML-T1
CML-T1
Detroit562
Detroit562
JURL-MK1
JURL-MK1
SUIT-2
SUIT-2
HCC-95
HCC-95
SHP-77
SHP-77
SNU-1066
SNU-1066
NCI-H2405
NCI-H2405
SU-DHL-1
SU-DHL-1
P12-ICHIKAWA
P12-ICHIKAWA
SNU-119
SNU-119
MOLM-13
MOLM-13
KURAMOCHI
KURAMOCHI
P31-FUJ
P31-FUJ
SNU-1077
SNU-1077
KU812
KU812
NCI-H1581
NCI-H1581
SNU-489
SNU-489
DOV13
DOV13
WSU-DLCL2
WSU-DLCL2
TUHR4TKB
TUHR4TKB
NCO2
NCO2
SNU-5
SNU-5
KHM-1B
KHM-1B
EM-2
EM-2
NCI-H2106
NCI-H2106
JVM-3
JVM-3
NCI-H526
NCI-H526
KMS-21BM
KMS-21BM
RPMI-7951
RPMI-7951
SNU-466
SNU-466
RH-41
RH-41
KMS-26
KMS-26
NCI-H1299
SBC-5
U-2-OS
MEL-HO
SNU-1041
JIMT-1
NCI-H292
COLO-205
EHEB
KMS-27
SNU-1076
NCI-N87
VM-CUB-1
RL95-2
PEER
KMM-1
RPMI-8402
KE-37
SNU-1196
CML-T1
Detroit562
JURL-MK1
SUIT-2
HCC-95
SHP-77
SNU-1066
NCI-H2405
SU-DHL-1
P12-ICHIKAWA
SNU-119
MOLM-13
KURAMOCHI
P31-FUJ
SNU-1077
KU812
NCI-H1581
SNU-489
DOV13
WSU-DLCL2
TUHR4TKB
NCO2
SNU-5
KHM-1B
EM-2
NCI-H2106
JVM-3
NCI-H526
KMS-21BM
RPMI-7951
SNU-466
RH-41
KMS-26
NCI-H1299: 15.01 (log10 µM)
Synonyms: NCI-H1299, NCIH1299
SBC-5: 12.11 (log10 µM)
Synonyms: SBC-5, SBC5
U-2-OS: 8.18 (log10 µM)
Synonyms: U-2-OS, U-2 OS, U-2_OS, U2OS
MEL-HO: 6.45 (log10 µM)
Synonyms: MEL-HO, MELHO
SNU-1041: 6.37 (log10 µM)
Synonyms: SNU-1041, SNU1041
JIMT-1: 6.00 (log10 µM)
Synonyms: JIMT-1, JIMT1, jimt1
NCI-H292: 5.44 (log10 µM)
Synonyms: NCI-H292, H292
COLO-205: 5.26 (log10 µM)
Synonyms: COLO-205, COLO 205, COLO205
EHEB: 4.31 (log10 µM)
Synonyms: EHEB
KMS-27: 3.78 (log10 µM)
Synonyms: KMS-27, KMS27
SNU-1076: 3.69 (log10 µM)
Synonyms: SNU-1076, SNU1076
NCI-N87: 3.59 (log10 µM)
Synonyms: NCI-N87, NCIN87
VM-CUB-1: 3.47 (log10 µM)
Synonyms: VM-CUB-1, VM-CUB1, VMCUB1
RL95-2: 2.81 (log10 µM)
Synonyms: RL95-2, RL952
PEER: 2.69 (log10 µM)
Synonyms: PEER
KMM-1: 2.64 (log10 µM)
Synonyms: KMM-1, KMM1
RPMI-8402: 2.50 (log10 µM)
Synonyms: RPMI-8402, RPMI8402
KE-37: 2.29 (log10 µM)
Synonyms: KE-37, KE37
SNU-1196: 2.27 (log10 µM)
Synonyms: SNU-1196, SNU1196
CML-T1: 2.26 (log10 µM)
Synonyms: CML-T1, CMLT1
Detroit562: 2.26 (log10 µM)
Synonyms: Detroit562, Detroit 562, Detroit_562, DETROIT562
JURL-MK1: 2.23 (log10 µM)
Synonyms: JURL-MK1, JURLMK1
SUIT-2: 2.18 (log10 µM)
Synonyms: SUIT-2, SUIT2
HCC-95: 2.17 (log10 µM)
Synonyms: HCC-95, HCC95
SHP-77: 2.15 (log10 µM)
Synonyms: SHP-77, SHP77
SNU-1066: 2.14 (log10 µM)
Synonyms: SNU-1066, SNU1066
NCI-H2405: 2.12 (log10 µM)
Synonyms: NCI-H2405, NCIH2405
SU-DHL-1: 2.09 (log10 µM)
Synonyms: SU-DHL-1, SUDHL1
P12-ICHIKAWA: 2.08 (log10 µM)
Synonyms: P12-ICHIKAWA, P12ICHIKAWA
SNU-119: 2.08 (log10 µM)
Synonyms: SNU-119, SNU119
MOLM-13: 2.07 (log10 µM)
Synonyms: MOLM-13, MOLM13
KURAMOCHI: 2.06 (log10 µM)
Synonyms: KURAMOCHI
P31-FUJ: 2.03 (log10 µM)
Synonyms: P31-FUJ, P31/FUJ, P31_FUJ, P31FUJ
SNU-1077: 2.02 (log10 µM)
Synonyms: SNU-1077, SNU1077
KU812: 2.01 (log10 µM)
Synonyms: KU812
NCI-H1581: 2.00 (log10 µM)
Synonyms: NCI-H1581, NCIH1581
SNU-489: 1.97 (log10 µM)
Synonyms: SNU-489, SNU489
DOV13: 1.96 (log10 µM)
Synonyms: DOV13
WSU-DLCL2: 1.96 (log10 µM)
Synonyms: WSU-DLCL2, WSUDLCL2
TUHR4TKB: 1.95 (log10 µM)
Synonyms: TUHR4TKB
NCO2: 1.95 (log10 µM)
Synonyms: NCO2
SNU-5: 1.93 (log10 µM)
Synonyms: SNU-5, SNU5
KHM-1B: 1.93 (log10 µM)
Synonyms: KHM-1B, KHM1B
EM-2: 1.93 (log10 µM)
Synonyms: EM-2, EM2
NCI-H2106: 1.93 (log10 µM)
Synonyms: NCI-H2106, NCIH2106
JVM-3: 1.91 (log10 µM)
Synonyms: JVM-3, JVM3
NCI-H526: 1.74 (log10 µM)
Synonyms: NCI-H526, NCIH526
KMS-21BM: 1.73 (log10 µM)
Synonyms: KMS-21BM, KMS21BM
RPMI-7951: 1.66 (log10 µM)
Synonyms: RPMI-7951, RPMI7951
SNU-466: 1.40 (log10 µM)
Synonyms: SNU-466, SNU466
RH-41: 1.34 (log10 µM)
Synonyms: RH-41, RH41
KMS-26: 1.31 (log10 µM)
Synonyms: KMS-26, KMS26
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
BRD-K58730230: AAC
AAC
Tissues
0.00
0.05
0.10
0.15
0.20
0.25
salivary_gland
salivary_gland
skin
skin
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
ovary
ovary
soft_tissue
soft_tissue
biliary_tract
biliary_tract
urinary_tract
urinary_tract
lung
lung
kidney
kidney
bone
bone
liver
liver
pancreas
pancreas
upper_aerodigestive_tract
upper_aerodigestive_tract
prostate
prostate
oesophagus
oesophagus
pleura
pleura
endometrium
endometrium
stomach
stomach
breast
breast
central_nervous_system
central_nervous_system
large_intestine
large_intestine
thyroid
thyroid
1.50
2.00
2.50
3.00
3.50
4.00
4.50
5.00
5.50
pleura
pleura
prostate
prostate
salivary_gland
salivary_gland
pancreas
pancreas
soft_tissue
soft_tissue
kidney
kidney
central_nervous_system
central_nervous_system
ovary
ovary
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
lung
lung
biliary_tract
biliary_tract
urinary_tract
urinary_tract
stomach
stomach
large_intestine
large_intestine
breast
breast
thyroid
thyroid
skin
skin
liver
liver
oesophagus
oesophagus
endometrium
endometrium
upper_aerodigestive_tract
upper_aerodigestive_tract
bone
bone
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to BRD-K58730230
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
FOXJ2
CTRPv2
pan-cancer
AAC
-0.13
0.07
mRNA
STRC
CTRPv2
pan-cancer
AAC
0.13
0.07
mRNA
TPTE
CTRPv2
pan-cancer
AAC
0.17
0.07
mRNA
ENY2
CTRPv2
pan-cancer
AAC
-0.14
0.07
mRNA
RNPS1
CTRPv2
pan-cancer
AAC
-0.14
0.07
mRNA
PLOD1
CTRPv2
pan-cancer
AAC
0.15
0.07
mRNA
ZIK1
CTRPv2
pan-cancer
AAC
-0.14
0.07
mRNA
GJC3
CTRPv2
pan-cancer
AAC
0.13
0.07
mRNA
WDYHV1
CTRPv2
pan-cancer
AAC
-0.13
0.07
mRNA
ZNF281
CTRPv2
pan-cancer
AAC
-0.15
0.07
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