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OSI-027

Synonyms

SourcesNames Used
GDSC1000, CTRPv2OSI-027
PharmacoGx OSI-027

External IDs

DatabaseIdentifier
Smiles: COc1cccc2cc([nH]c12)-c1nc([C@@H]2CC[C@@H](CC2)C(O)=O)n2ncnc(N)c12
Pubchem: 44224160

Annotated Targets

MTOR

FDA Approval Status

Not Approved
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Top molecular features associated with response to OSI-027


Feature TypeStandardized
Nominal ANOVA
mRNA C20orf96 GDSC1000 pan-cancer AAC 0.14 1e-05
mRNA EPS8 GDSC1000 pan-cancer AAC -0.16 1e-05
mRNA PCDH17 GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA LRRC4C GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA RBBP4 GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA SIRT1 GDSC1000 pan-cancer AAC 0.14 1e-05
mRNA THRAP3 GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA HOXD10 GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA KDELR3 GDSC1000 pan-cancer AAC -0.18 1e-05
mRNA RAB31 GDSC1000 pan-cancer AAC -0.16 1e-05
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