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OSI-027

Synonyms

SourcesNames Used
GDSC1000, CTRPv2OSI-027
PharmacoGx OSI-027

External IDs

DatabaseIdentifier
Smiles: COc1cccc2cc([nH]c12)-c1nc([C@@H]2CC[C@@H](CC2)C(O)=O)n2ncnc(N)c12
Pubchem: 44224160

Annotated Targets

MTOR

FDA Approval Status

Not Approved
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Top molecular features associated with response to OSI-027


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF92 GDSC1000 pan-cancer AAC 0.16 3e-06
mRNA RBM38 GDSC1000 pan-cancer AAC 0.16 3e-06
mRNA BCAR3 GDSC1000 pan-cancer AAC -0.17 3e-06
mRNA RPAIN GDSC1000 pan-cancer AAC 0.15 3e-06
mRNA PPP1R1A GDSC1000 pan-cancer AAC 0.17 3e-06
mRNA TBCC GDSC1000 pan-cancer AAC 0.15 3e-06
mRNA CYYR1 GDSC1000 pan-cancer AAC 0.16 3e-06
mRNA STK17A GDSC1000 pan-cancer AAC -0.16 3e-06
mRNA MED13 GDSC1000 pan-cancer AAC 0.15 3e-06
mRNA ACTN2 GDSC1000 pan-cancer AAC 0.17 4e-06
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