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OSI-027

Synonyms

SourcesNames Used
GDSC1000, CTRPv2OSI-027
PharmacoGx OSI-027

External IDs

DatabaseIdentifier
Smiles: COc1cccc2cc([nH]c12)-c1nc([C@@H]2CC[C@@H](CC2)C(O)=O)n2ncnc(N)c12
Pubchem: 44224160

Annotated Targets

MTOR

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to OSI-027


Feature TypeStandardized
Nominal ANOVA
mRNA AVPI1 GDSC1000 pan-cancer AAC -0.18 4e-06
mRNA FUCA2 GDSC1000 pan-cancer AAC -0.17 4e-06
mRNA SH2D4A GDSC1000 pan-cancer AAC -0.17 4e-06
mRNA FAM177A1 GDSC1000 pan-cancer AAC -0.18 4e-06
mRNA HRH1 GDSC1000 pan-cancer AAC -0.16 4e-06
mRNA SQRDL GDSC1000 pan-cancer AAC -0.16 4e-06
mRNA TIMM13 GDSC1000 pan-cancer AAC 0.15 4e-06
mRNA ZNF91 GDSC1000 pan-cancer AAC 0.15 4e-06
mRNA CUX2 GDSC1000 pan-cancer AAC 0.16 4e-06
mRNA LPP GDSC1000 pan-cancer AAC -0.16 4e-06
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