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KW-2449

KW-2449

Synonyms

Sources	Names Used
CTRPv2	KW-2449
PharmacoGx	KW-2449

External IDs

Database	Identifier
Pubchem:	11427553

Annotated Targets

ABL1, AURKA, AURKB, FLT3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to KW-2449

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GMFG	CTRPv2	pan-cancer	AAC	0.29	6e-12
mRNA	ITGAL	CTRPv2	pan-cancer	AAC	0.26	6e-15
mRNA	SPN	CTRPv2	pan-cancer	AAC	0.25	1e-09
mRNA	PRSS57	CTRPv2	pan-cancer	AAC	0.24	3e-16
mRNA	TOP1MT	CTRPv2	pan-cancer	AAC	0.24	6e-14
mRNA	ARHGAP4	CTRPv2	pan-cancer	AAC	0.23	3e-08
mRNA	DOT1L	CTRPv2	pan-cancer	AAC	0.23	2e-09
mRNA	MEX3A	CTRPv2	pan-cancer	AAC	0.23	2e-09
mRNA	ARHGAP45	CTRPv2	pan-cancer	AAC	0.22	3e-07
mRNA	LAIR1	CTRPv2	pan-cancer	AAC	0.22	1e-10

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