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KW-2449

KW-2449

Synonyms

Sources	Names Used
CTRPv2	KW-2449
PharmacoGx	KW-2449

External IDs

Database	Identifier
Pubchem:	11427553

Annotated Targets

ABL1, AURKA, AURKB, FLT3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to KW-2449

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	E2F3	CTRPv2	pan-cancer	AAC	0.17	6e-08
mRNA	TRIM65	CTRPv2	pan-cancer	AAC	0.17	6e-08
mRNA	MS4A6A	CTRPv2	pan-cancer	AAC	0.16	6e-08
mRNA	SF3A2	CTRPv2	pan-cancer	AAC	0.18	7e-08
mRNA	SAFB	CTRPv2	pan-cancer	AAC	0.19	8e-08
mRNA	APOC4-APOC2	CTRPv2	pan-cancer	AAC	0.16	8e-08
mRNA	SIRT1	CTRPv2	pan-cancer	AAC	0.17	8e-08
mRNA	FRY	CTRPv2	pan-cancer	AAC	0.16	8e-08
mRNA	DENND6A	CTRPv2	pan-cancer	AAC	0.16	8e-08
mRNA	PRR3	CTRPv2	pan-cancer	AAC	0.19	8e-08

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