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KW-2449

KW-2449

Synonyms

Sources	Names Used
CTRPv2	KW-2449
PharmacoGx	KW-2449

External IDs

Database	Identifier
Pubchem:	11427553

Annotated Targets

ABL1, AURKA, AURKB, FLT3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to KW-2449

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	IL3RA	CTRPv2	pan-cancer	AAC	0.17	4e-08
mRNA	APOC2	CTRPv2	pan-cancer	AAC	0.16	4e-08
mRNA	TAF5	CTRPv2	pan-cancer	AAC	0.19	4e-08
mRNA	ZBED4	CTRPv2	pan-cancer	AAC	0.19	5e-08
mRNA	ANP32B	CTRPv2	pan-cancer	AAC	0.19	5e-08
mRNA	N4BP2L1	CTRPv2	pan-cancer	AAC	0.2	5e-08
mRNA	TMEM159	CTRPv2	pan-cancer	AAC	-0.18	6e-08
mRNA	COQ8A	CTRPv2	pan-cancer	AAC	0.18	6e-08
mRNA	CTB-54O9.9	CTRPv2	pan-cancer	AAC	0.18	6e-08
mRNA	ZBTB3	CTRPv2	pan-cancer	AAC	0.18	6e-08

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