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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF554	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	TMOD2	CTRPv2	pan-cancer	AAC	0.16	0.0001
mRNA	EDAR	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	FAM71E1	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	LMO1	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	PCNP	CTRPv2	pan-cancer	AAC	-0.14	0.0002
mRNA	RP11-140L24.4	CTRPv2	pan-cancer	AAC	-0.14	0.0002
mRNA	BMP3	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	BTC	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	ABTB1	CTRPv2	pan-cancer	AAC	0.14	0.0002

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