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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RABEP1	CTRPv2	pan-cancer	AAC	-0.13	0.0009
mRNA	MRPL1	CTRPv2	pan-cancer	AAC	-0.13	0.0009
mRNA	GTPBP4	CTRPv2	pan-cancer	AAC	-0.12	0.0009
mRNA	ROS1	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	CES2	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	PRDX3	CTRPv2	pan-cancer	AAC	-0.13	0.0009
mRNA	MYH9	CTRPv2	pan-cancer	AAC	0.13	0.001
mRNA	CORIN	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	KCNJ4	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	DTX4	CTRPv2	pan-cancer	AAC	0.13	0.001

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