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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TGFBI	CTRPv2	pan-cancer	AAC	0.11	0.008
mRNA	ST8SIA2	CTRPv2	pan-cancer	AAC	0.12	0.008
mRNA	SASH3	CTRPv2	pan-cancer	AAC	0.12	0.008
mRNA	COL10A1	CTRPv2	pan-cancer	AAC	0.098	0.008
mRNA	MMP9	CTRPv2	pan-cancer	AAC	0.096	0.008
mRNA	PACS2	CTRPv2	pan-cancer	AAC	0.1	0.008
mRNA	PARP6	CTRPv2	pan-cancer	AAC	0.1	0.008
mRNA	PLGRKT	CTRPv2	pan-cancer	AAC	-0.097	0.008
mRNA	NHP2	CTRPv2	pan-cancer	AAC	-0.099	0.008
mRNA	ST6GALNAC5	CTRPv2	pan-cancer	AAC	0.1	0.008

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