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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CTAGE4	CTRPv2	pan-cancer	AAC	0.12	0.007
mRNA	KLF12	CTRPv2	pan-cancer	AAC	0.1	0.007
mRNA	BCAT1	CTRPv2	pan-cancer	AAC	0.099	0.007
mRNA	GPRIN1	CTRPv2	pan-cancer	AAC	0.11	0.007
mRNA	C16orf92	CTRPv2	pan-cancer	AAC	0.11	0.007
mRNA	SLC16A13	CTRPv2	pan-cancer	AAC	-0.1	0.007
mRNA	CASP5	CTRPv2	pan-cancer	AAC	0.1	0.007
mRNA	IRGC	CTRPv2	pan-cancer	AAC	0.099	0.007
mRNA	MPRIP	CTRPv2	pan-cancer	AAC	0.1	0.007
mRNA	MMD2	CTRPv2	pan-cancer	AAC	0.098	0.007

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