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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	LGALS4	CTRPv2	pan-cancer	AAC	0.12	0.004
mRNA	YPEL1	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	POFUT1	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	TMEM80	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	SMAD1	CTRPv2	pan-cancer	AAC	0.1	0.004
mRNA	ESF1	CTRPv2	pan-cancer	AAC	-0.1	0.004
mRNA	APOOL	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	HLA-DMA	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	CCNI2	CTRPv2	pan-cancer	AAC	0.1	0.004
mRNA	ATG3	CTRPv2	pan-cancer	AAC	-0.11	0.004

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