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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GSKIP	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	ALDH1L1	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	METAP2	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	TPST1	CTRPv2	pan-cancer	AAC	0.13	0.004
mRNA	BCS1L	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	PTPRU	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	FOXN2	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	EPPIN-WFDC6	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	TXN2	CTRPv2	pan-cancer	AAC	-0.12	0.004
mRNA	TLN2	CTRPv2	pan-cancer	AAC	0.11	0.004

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