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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RP1-172N19.1	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	ST20	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	GPR155	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	ATP5C1	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	MRPL41	CTRPv2	pan-cancer	AAC	-0.12	0.002
mRNA	IARS2	CTRPv2	pan-cancer	AAC	-0.12	0.002
mRNA	NOP10	CTRPv2	pan-cancer	AAC	-0.11	0.003
mRNA	PDC	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	RP11-624J6.2	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	LINC00684	CTRPv2	pan-cancer	AAC	0.11	0.003

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