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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF17	CTRPv2	pan-cancer	AAC	0.092	0.02
mRNA	IL1RL1	CTRPv2	pan-cancer	AAC	0.087	0.02
mRNA	PRSS54	CTRPv2	pan-cancer	AAC	0.088	0.02
mRNA	HIVEP3	CTRPv2	pan-cancer	AAC	0.091	0.02
mRNA	PDHB	CTRPv2	pan-cancer	AAC	-0.092	0.02
mRNA	TMEM170A	CTRPv2	pan-cancer	AAC	-0.092	0.02
mRNA	NDUFAF2	CTRPv2	pan-cancer	AAC	-0.087	0.02
mRNA	APOE	CTRPv2	pan-cancer	AAC	-0.088	0.02
mRNA	MPZ	CTRPv2	pan-cancer	AAC	0.089	0.02
mRNA	OXLD1	CTRPv2	pan-cancer	AAC	-0.087	0.02

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