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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RASD2	CTRPv2	pan-cancer	AAC	0.088	0.02
mRNA	IRAK2	CTRPv2	pan-cancer	AAC	0.09	0.02
mRNA	PPM1E	CTRPv2	pan-cancer	AAC	0.099	0.02
mRNA	IPO7	CTRPv2	pan-cancer	AAC	-0.089	0.02
mRNA	CHRNB2	CTRPv2	pan-cancer	AAC	0.094	0.02
mRNA	FOXL2NB	CTRPv2	pan-cancer	AAC	-0.088	0.02
mRNA	SLC25A5	CTRPv2	pan-cancer	AAC	-0.09	0.02
mRNA	MIER3	CTRPv2	pan-cancer	AAC	0.088	0.02
mRNA	TBX6	CTRPv2	pan-cancer	AAC	0.09	0.02
mRNA	OSGEPL1	CTRPv2	pan-cancer	AAC	-0.089	0.02

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