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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CTAGE8	CTRPv2	pan-cancer	AAC	0.14	0.003
mRNA	RAX2	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	MRPL30	CTRPv2	pan-cancer	AAC	-0.11	0.003
mRNA	SNX3	CTRPv2	pan-cancer	AAC	-0.11	0.003
mRNA	GIMAP1-GIMAP5	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	DLAT	CTRPv2	pan-cancer	AAC	-0.11	0.003
mRNA	CDH2	CTRPv2	pan-cancer	AAC	0.13	0.003
mRNA	NRXN2	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	BOLL	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	SIX6	CTRPv2	pan-cancer	AAC	0.11	0.003

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