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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PDGFA	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	EHF	CTRPv2	pan-cancer	AAC	0.14	0.001
mRNA	MRPS9	CTRPv2	pan-cancer	AAC	-0.12	0.001
mRNA	CTAGE15	CTRPv2	pan-cancer	AAC	0.14	0.002
mRNA	PPEF1	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	MEX3C	CTRPv2	pan-cancer	AAC	0.13	0.002
mRNA	FBXW4	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	THBS1	CTRPv2	pan-cancer	AAC	0.13	0.002
mRNA	ZNF862	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	RAP2C	CTRPv2	pan-cancer	AAC	-0.12	0.002

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