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clofarabine

Synonyms

SourcesNames Used
CTRPv2clofarabine
PharmacoGx clofarabine

External IDs

DatabaseIdentifier
Smiles: Nc1nc(Cl)nc2n(cnc12)C3OC(CO)C(O)C3F
Inchikey: WDDPHFBMKLOVOX-UHFFFAOYSA-N
Pubchem: 119182

Annotated Targets

POLA1, POLD1, POLE, RRM1, RRM2, RRM2B

FDA Approval Status

Approved
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Top molecular features associated with response to clofarabine


Feature TypeStandardized
Nominal ANOVA
mRNA CMTM2 CTRPv2 pan-cancer AAC 0.1 0.0003
mRNA SLC19A1 CTRPv2 pan-cancer AAC 0.11 0.0003
mRNA TOMM5 CTRPv2 pan-cancer AAC 0.1 0.0003
mRNA ACBD3 CTRPv2 pan-cancer AAC -0.11 0.0003
mRNA CFAP20 CTRPv2 pan-cancer AAC 0.1 0.0003
mRNA TMIGD3 CTRPv2 pan-cancer AAC -0.1 0.0004
mRNA PPP2R5B CTRPv2 pan-cancer AAC -0.11 0.0004
mRNA ARHGEF6 CTRPv2 pan-cancer AAC 0.12 0.0004
mRNA PRRG2 CTRPv2 pan-cancer AAC -0.13 0.0004
mRNA PRMT6 CTRPv2 pan-cancer AAC 0.11 0.0004
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