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clofarabine

clofarabine

Synonyms

Sources	Names Used
CTRPv2	clofarabine
PharmacoGx	clofarabine

External IDs

Database	Identifier
Smiles:	Nc1nc(Cl)nc2n(cnc12)C3OC(CO)C(O)C3F
Inchikey:	WDDPHFBMKLOVOX-UHFFFAOYSA-N
Pubchem:	119182

Annotated Targets

POLA1, POLD1, POLE, RRM1, RRM2, RRM2B

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to clofarabine

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CD3G	CTRPv2	pan-cancer	AAC	0.093	0.001
mRNA	COL8A1	CTRPv2	pan-cancer	AAC	-0.098	0.001
mRNA	SLC17A5	CTRPv2	pan-cancer	AAC	-0.098	0.001
mRNA	SLC35B3	CTRPv2	pan-cancer	AAC	-0.094	0.001
mRNA	GABARAPL1	CTRPv2	pan-cancer	AAC	-0.096	0.001
mRNA	TMEM70	CTRPv2	pan-cancer	AAC	0.094	0.001
mRNA	SETD1B	CTRPv2	pan-cancer	AAC	0.097	0.001
mRNA	NAF1	CTRPv2	pan-cancer	AAC	0.095	0.001
mRNA	GUF1	CTRPv2	pan-cancer	AAC	0.097	0.001
mRNA	KLHL25	CTRPv2	pan-cancer	AAC	0.098	0.001

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